Protein Alignment lok and dclk2

DIOPT Version :10

• Sequence 1: NP_477219.1
• Gene: lok / 35288
• FlyBaseID: FBgn0019686
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: XP_012811056.1
• Gene: dclk2 / 100487296
• XenbaseID: XB-GENE-960488
• Length: 727
• Species: Xenopus tropicalis
• Alignment Length: 297
• Identity: 96/297 - (32%)
• Similarity: 155/297 - (52%)
• Gaps: 27/297 - (9%)

  Fly   161 NESIGLPEEIN-----------KTYYVNRKLGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGAR 214
            |..:..||.:|           :.|.:.:.:|.|.:.:|:...:..|.::||:||:.|....|..
 Frog   374 NGLLNSPEGLNGNKFTDASIILEKYKIGKVIGDGNFAVVKECVERSTGKEFALKIIDKAKCCGKE 438

  Fly   215 PSTNFSDPDRVLNEAKIMKNLSHPCVVRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDI 279
                    ..:.||..|::.:.||.::.:.:.:|....:|:|:|.::||||.:.|.|:...:|..
 Frog   439 --------HLIENEVSILRQVKHPNIIMLIEEMDTTAELYLVMELVKGGDLFDAITSSTKYTERD 495

  Fly   280 SKLYFYQMCHAVKYLHDRGITHRDLKPDNVLL-ETNDEETLLKVSDFGLSKFVQKDSVMRTLCGT 343
            :....|.:..|:||||...|.|||:||:|:|: |..|:...||:.||||:..|  |..:.|:|||
 Frog   496 ASAMVYNLASAMKYLHGLHIVHRDIKPENLLVCEYPDKTKSLKLGDFGLATVV--DGPLYTVCGT 558

  Fly   344 PLYVAPEVLITGGREAYTKKVDIWSLGVVLFTCLSGTLPFSDEYG--TPAAQQIKKGRFAYGHPS 406
            |.|||||::...|   |..|||||:.||:.:..|.|..||..|..  .....||..|:..:..|.
 Frog   559 PTYVAPEIIAETG---YGLKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILIGKLEFPSPY 620

  Fly   407 WKSVSQRAKLLINQMLIVDPERRPSIDDVLQSSWLRD 443
            |.:::..||.||:.||.|:.|.|.:.:.:|...|:.|
 Frog   621 WDNITDSAKELISCMLQVNVEERYTAEQILSHPWVSD 657

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lok	NP_477219.1	FHA_CHK2	32..158	CDD:438718
		STKc_Chk2	167..441	CDD:270986	93/287 (32%)
dclk2	XP_012811056.1	DCX1_DCLK2	70..154	CDD:340661
		DCX2	193..276	CDD:340589
		STKc_DCKL2	396..654	CDD:271086	90/270 (33%)