DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lok and si:ch73-60h1.1

DIOPT Version :9

Sequence 1:	NP_477219.1	Gene:	lok / 35288	FlyBaseID:	FBgn0019686	Length:	476	Species:	Drosophila melanogaster
Sequence 2:	XP_002663771.2	Gene:	si:ch73-60h1.1 / 100332381	ZFINID:	ZDB-GENE-140106-152	Length:	438	Species:	Danio rerio

Alignment Length:	294	Identity:	98/294 - (33%)
Similarity:	162/294 - (55%)	Gaps:	20/294 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   174 YYVNRKLGSGAYGLVRLVYDTRTCQQFAMKIVKKNMLSGARPSTNFSDPDRVLNEAKIMKNLSHP 238
            |.:..:||.||..:|....:.:|.:.:|:|::||.:           |...|..|..::..||||
Zfish    28 YNMGPELGRGATSVVLRCEEKQTEKPYAVKVLKKTI-----------DKKIVRTEIGVLLRLSHP 81

  Fly   239 CVVRMHDIVDKPDSVYMVLEFMRGGDLLNRIISNKLLSEDISKLYFYQMCHAVKYLHDRGITHRD 303
            .::|:.:|.:....::::||.:.||:|.:||:.....||..:.....|:..||.|||:.|:.|||
Zfish    82 NIIRLKEIFETETEIFLILELVTGGELFDRIVERGYYSERDAAHVIKQILEAVAYLHENGVVHRD 146

  Fly   304 LKPDNVLLETNDEETLLKVSDFGLSKFVQKDSVMRTLCGTPLYVAPEVLITGGREAYTKKVDIWS 368
            |||:|:|......:..||::||||||.:.:...|:|:||||.|.|||:|   ...||..:||:||
Zfish   147 LKPENLLYADLSIDAPLKIADFGLSKIIDEQVTMKTVCGTPGYCAPEIL---RGNAYGPEVDMWS 208

  Fly   369 LGVVLFTCLSGTLPFSDEYGTP-AAQQIKKGRFAYGHPSWKSVSQRAKLLINQMLIVDPERRPSI 432
            :||:|:..|.|..||.|:.|.. ...:|....:.:..|.|..||..||.|:|:::::||.:|.::
Zfish   209 VGVILYILLCGFEPFFDQRGDQYMYSRILNCDYEFVSPWWDEVSLNAKDLVNKLIVLDPHKRLTV 273

  Fly   433 DDVLQSSWLRDAPMLQKAKRLMKLDGMEIEEENF 466
            ...|:..|     :|.||.|...:|..:.:.:.|
Zfish   274 KQALEHPW-----VLGKAARFSHMDTTQRKLQEF 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lok	NP_477219.1	FHA	39..156	CDD:238017
		STKc_Chk2	167..441	CDD:270986	91/267 (34%)
		S_TKc	174..441	CDD:214567	91/267 (34%)
si:ch73-60h1.1	XP_002663771.2	STKc_CaMKIV	24..317	CDD:270987	98/294 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910