Protein Alignment barr and Ncaph

DIOPT Version :10

• Sequence 1: NP_477106.1
• Gene: barr / 35287
• FlyBaseID: FBgn0014127
• Length: 735
• Species: Drosophila melanogaster
• Sequence 2: NP_659067.2
• Gene: Ncaph / 215387
• MGIID: 2444777
• Length: 731
• Species: Mus musculus
• Alignment Length: 832
• Identity: 207/832 - (24%)
• Similarity: 329/832 - (39%)
• Gaps: 203/832 - (24%)

  Fly     1 MTLPRLET-----------------PLRR----SAVGSYQEGVSRMLT----PFNDDEAERREAR 40
            |.:||.||                 ||.|    |..|....|..:...    |.||||.||.:.|
Mouse     1 MRIPRSETMNSSFLKARGQQDVLSSPLERVPPASRPGKAPLGTPKTPVLEDFPQNDDEKERMQRR 65

  Fly    41 RRTLLQQH------HRSSTLESIEDNETI------------KNCLELYNGNKVSKDNAWNLMLID 87
            |..:....      |.:|...:|:.:.||            ..|::|.:.||::..||:.|.|||
Mouse    66 RSRVFDLQFSTDSIHLASPNRNIDVSTTISKFTNTQITEHYSTCIKLSSENKITTKNAFGLHLID 130

  Fly    88 SLANLLDHHHKRMSNFKMAGSSLEASSKVYGLRVDSIYLDAMRISAGLSARTLTDKQINAAEDDD 152
            .::.:|.......:|||:|..:|:||:|:|.:|||:::.|..|:..||.             .|.
Mouse   131 FMSEILKQKDAEPTNFKVAAGTLDASTKIYAVRVDAVHADVYRVLGGLG-------------KDT 182

  Fly   153 GPQGEQA-TGEGQDSAQQAAKEAAPKPKRQKKPISTVTKNRETLN-SRLDTAPLQDPVFGKLNST 215
            .||||:: :|:|.....:..|:.| |||: |:...|:.:|...:| |..|.....||:|.|..::
Mouse   183 PPQGEESHSGDGSTLETERTKKPA-KPKK-KQSCKTIEQNLSNINVSEADGKCAVDPMFQKTAAS 245

  Fly   216 VGSINASNRLMHNI-LPSFDSELRLRTTYNFWNSEESTE----EVQDHTTLNAEMEQWPATSLMS 275
            ....:.:...:..: ...:.|||...:.....:|.|..|    ...|.|.|.|.::|.
Mouse   246 FDECSTTGVFLSTLHCQDYRSELLFPSDMQTLSSGEPLELPDLGFVDMTDLEASLQQC------- 303

  Fly   276 TNLMRKLLPHAERSNLRPLHTGYIITSAPNPKSANEKAAEVVQDEDHDEGLDNADDMCVNEISMA 340
                      .|...|.|...|:..|.              ...|.|:|.:....|. ..:....
Mouse   304 ----------VEDRPLCPSLAGFQFTK--------------WDSETHNESVSALVDK-FKKNDQV 343

  Fly   341 FDINAEC----EPMPDLDGPPPLVLEVDSNELEELTA-------------------EEQMVINNC 382
            ||||||.    |.:||    .|||.:...|:..:|:|                   :|:::....
Mouse   344 FDINAEAEDDEEDVPD----GPLVEDFVDNDEPDLSAAGDHEEFRSWKELCQVQSNQEEVISLED 404

  Fly   383 RRLRKQTEFIEDLRPVDGNSKLEYSY---RPMDQISQFWAGPSHWKFKRTRPRSTFSQTNGQVDT 444
            |.::....|: .::|.      ||||   |.|    :.||||.||:| |.||:...:.....
Mouse   405 RDIQVMCSFL-SMKPG------EYSYFSPRTM----KMWAGPDHWRF-RPRPKQDATSCTEH--- 454

  Fly   445 QPIRTQRAKKSAHLNANRRAKALDYGNVTENFFQQLD-TTIRQRKANFQKKWDPRKLILPTKFEL 508
               :.:.|||...:|.:   ..:|:    :.:||:.. .||..:.....:.|  :...|||.|..
Mouse   455 ---KKKSAKKDFEINFD---DDIDF----DAYFQKTKAATILTKSTLENQNW--KATTLPTDFHY 507

  Fly   509 DPDLFFKYESAPSIKLSKRAGEPDSDEGGDLGIDMDADM-----HHDDDNDQELFNNEHFTDAVP 568
            :.|...:....|                |...:.||.|.     |:::..|.: :||.:.|
Mouse   508 ETDNLIQLHLKP----------------GKRSLKMDQDQKAKTEHYEEIEDYD-YNNPNDT---- 551

  Fly   569 ANVSVIAAIAAEQAAEASMMNVSAGEIG---------LTQMNA--TCNNTVFEIGTEFE----GA 618
            :|.......|.....||.  ::.|..:|         .||.|.  :..|...:|.|..|    ..
Mouse   552 SNYCPGLQAADSDYEEAD--DLFADPVGTLDLESDPKTTQENGHISPENQGVDITTYQELNLVAE 614

  Fly   619 PSQVAKVIVPFAKRAKVIDMKNLKKSCNSLIQKQLLNAVPEETIPSHPKKKGEHYSKGFASFQQV 683
            |.:|.|:.:.:||.||.:|||.||:|..||:.|  .:....:|..:|.:...|...:..|..:::
Mouse   615 PQKVNKIEIHYAKTAKKMDMKKLKQSMWSLLTK--FSRKEADTEANHTESGQEGAPEEVADEKKL 677

  Fly   684 YQKLPDL---LTTKMSDSLSPSVAFYAVLHLANDLKLRLIPQEDLEDFQIRQ 732
            .....||   |...|:.:||..:||..:|||||:..|:|...|||.|..:.|
Mouse   678 SGLTKDLQTRLPPLMAQNLSIPLAFACLLHLANEKNLKLEGTEDLSDVLVMQ 729

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
barr	NP_477106.1	Cnd2	7..732	CDD:428627	203/824 (25%)
Ncaph	NP_659067.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..62		17/60 (28%)
		Cnd2	42..729	CDD:428627	196/789 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	178..214		14/50 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	652..673		3/20 (15%)