DRSC/TRiP Functional Genomics Resources

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Protein Alignment COX4 and COX5B

DIOPT Version :9

Sequence 1:NP_001260612.1 Gene:COX4 / 35279 FlyBaseID:FBgn0032833 Length:182 Species:Drosophila melanogaster
Sequence 2:NP_012155.1 Gene:COX5B / 854695 SGDID:S000001373 Length:151 Species:Saccharomyces cerevisiae


Alignment Length:174 Identity:36/174 - (20%)
Similarity:61/174 - (35%) Gaps:50/174 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 LASQLPKSAQVGSVAAVHT--LDKIGKREIVGYGWNGTACYADRVDYP-----LPAVRFREPTNE 71
            |.:.|.|.|::.....|.|  |.|                 |...|.|     :|.:..:|..:.
Yeast     2 LRTSLTKGARLTGTRFVQTKALSK-----------------ATLTDLPERWENMPNLEQKEIADN 49

  Fly    72 INALRAKEQGDWKKLSTQEIKALYRASFCQTIAEVQAGSGEW----KLHLGVSLLFCAAAIWVAV 132
               |..:::..||.|:.:||||.:..|:           |||    .:|....:.|....:::.:
Yeast    50 ---LTERQKLPWKTLNNEEIKAAWYISY-----------GEWGPRRPVHGKGDVAFITKGVFLGL 100

  Fly   133 --------LMNIFVYDELPVTFDEEHQKAQLQRIIDLEINPVTG 168
                    |:.:....|.|.|.:.|.|....:.:.....||..|
Yeast   101 GISFGLFGLVRLLANPETPKTMNREWQLKSDEYLKSKNANPWGG 144

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
COX4NP_001260612.1 COX4 50..181 CDD:281003 28/136 (21%)
COX5BNP_012155.1 Cyt_c_Oxidase_IV 18..151 CDD:238462 32/158 (20%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C157344617
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4075
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_103849
Panther 1 1.100 - - O PTHR10707
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R4386
SonicParanoid 1 1.000 - - X922
TreeFam 00.000 Not matched by this tool.
76.860

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