DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10481 and VTC3

DIOPT Version :9

Sequence 1:	NP_995731.1	Gene:	CG10481 / 35273	FlyBaseID:	FBgn0032827	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_015306.1	Gene:	VTC3 / 856088	SGDID:	S000005940	Length:	835	Species:	Saccharomyces cerevisiae

Alignment Length:	199	Identity:	50/199 - (25%)
Similarity:	71/199 - (35%)	Gaps:	60/199 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFGKTLDNLMVPEWRYQYMNYNELKQMIRNAVEKAPSGSRPSNDVAIGYYRNFEELFFNSCRVE 65
            |.||..|.|.:.|.|:..|::|..||::::   |......|.|.|   .:....|..|..:...|
Yeast     1 MLFGIKLANDVYPPWKDSYIDYERLKKLLK---ESVIHDGRSSVD---SWSERNESDFVEALDKE 59

  Fly    66 LTKVNYFFAHKQAEAHRKLATLNYQLDRRRAQQDPRGSTASRGSASSWSRQPEGKRKFPPIKKLR 130
            |.||..|...|.....|||..|.                             |..:....|:|:.
Yeast    60 LEKVYTFQISKYNAVLRKLDDLE-----------------------------ENTKSAEKIQKIN 95

  Fly   131 LAMSEFYLSLI--------MLQNYQTLNMTAFRKICKKYDK---NLKSEAGFAWYEKYVLKSTLA 184
               ||.:.:.:        .|.|:..||.|.|.||.||:||   |..|           :||.|.
Yeast    96 ---SEQFKNTLEECLDEAQRLDNFDRLNFTGFIKIVKKHDKLHPNYPS-----------VKSLLQ 146

  Fly   185 ITLQ 188
            :.|:
Yeast   147 VRLK 150

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10481	NP_995731.1	SPX_XPR1_like	2..163	CDD:269898	41/168 (24%)
		SPX	3..163	CDD:281146	41/167 (25%)
		EXS	267..601	CDD:281164
VTC3	NP_015306.1	COG5036	1..561	CDD:227369	50/199 (25%)
VTC3	NP_015306.1	VTC1	673..803	CDD:227589
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343542
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.569298	Normalized mean entropy	S1995
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.790