DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10481 and VTC4

DIOPT Version :9

Sequence 1:	NP_995731.1	Gene:	CG10481 / 35273	FlyBaseID:	FBgn0032827	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_012522.2	Gene:	VTC4 / 853441	SGDID:	S000003549	Length:	721	Species:	Saccharomyces cerevisiae

Alignment Length:	208	Identity:	47/208 - (22%)
Similarity:	84/208 - (40%)	Gaps:	45/208 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFGKTLDNLMVPEWRYQYMNYNELKQMIRNAVEKAPSGSRPSNDVAIGYYRNFEELFFNSCRVE 65
            ||||:.|...::.::.|.|::|::||..:.:.:.| .:|.         :.:..|..|..|..:|
Yeast     1 MKFGEHLSKSLIRQYSYYYISYDDLKTELEDNLSK-NNGQ---------WTQELETDFLESLEIE 55

  Fly    66 LTKVNYFFAHKQAEAHRKLATLNYQLDRRRAQQDPRGSTASRGSASSWSRQPEGKRKFPPIKKLR 130
            |.||..|...|.:|..|::..:..|:.......|              |..|..:..|..:::
Yeast    56 LDKVYTFCKVKHSEVFRRVKEVQEQVQHTVRLLD--------------SNNPPTQLDFEILEE-- 104

  Fly   131 LAMSEFYLSLIMLQNYQTLNMTAFRKICKKYDKNLKSEAGFAWYEKYVLKSTLAITL-------- 187
             .:|:....:..|..:..||.|.|:||.||:||    :.||      :||....:.|
Yeast   105 -ELSDIIADVHDLAKFSRLNYTGFQKIIKKHDK----KTGF------ILKPVFQVRLDSKPFFKE 158

  Fly   188 QLDRMISTTENMY 200
            ..|.::.....:|
Yeast   159 NYDELVVKISQLY 171

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10481	NP_995731.1	SPX_XPR1_like	2..163	CDD:269898	37/160 (23%)
		SPX	3..163	CDD:281146	36/159 (23%)
		EXS	267..601	CDD:281164
VTC4	NP_012522.2	COG5036	1..497	CDD:227369	47/208 (23%)
VTC4	NP_012522.2	DUF202	593..721	CDD:415817
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343553
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.569298	Normalized mean entropy	S1995
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.790