DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10481 and AT1G69480

DIOPT Version :9

Sequence 1:	NP_995731.1	Gene:	CG10481 / 35273	FlyBaseID:	FBgn0032827	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_001320450.1	Gene:	AT1G69480 / 843280	AraportID:	AT1G69480	Length:	777	Species:	Arabidopsis thaliana

Alignment Length:	805	Identity:	198/805 - (24%)
Similarity:	308/805 - (38%)	Gaps:	236/805 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFGKTLDNLMVPEWRYQYMNYNELKQMIR---------------------NAVEKAPSG----- 39
            |||||.....|||||...|::||.||::::                     .|:.::.||
plant     1 MKFGKIFKKQMVPEWVEAYVDYNGLKRVLKEIRSYKHSKLTRAASRVSQQAEALHRSFSGLSFHP 65

  Fly    40 --SRPSNDVAIGYYR-------------------------NFEELFFNSCRVELTKVNYFFAHKQ 77
              |..:.|:.....:                         .|||.||......|.|||.|:..|.
plant    66 RHSERAGDIEDQVIKVDTVQEEGSRKLYETKFLKKSEEGGEFEESFFKKLDENLNKVNKFYRDKV 130

  Fly    78 AEAHRKLATLNYQLDR----RRAQQDP--------------------RGSTASRGSASS------ 112
            .|...:.|.|:.|:|.    |...|.|                    ..:..::|:|::
plant   131 KEVIEEAALLDKQMDALIALRVKMQKPDVDNLNLEKHPSDKVVVDTSDNTMRTQGTANTDMVHGI 195

  Fly   113 ---------------------------------------------------------------WS 114
                                                                           .|
plant   196 ERTNIPEEEASHIMADIVPVSHTNGDEEEASIGDKQDLREILERVKMNDVLESPITTLKGVFGDS 260

  Fly   115 RQPEGKRKFPPIKK----LRLAMSEFYLSLIMLQNYQTLNMTAFRKICKKYDKNLKSEAGFAWYE 175
            .:|..|:   .:||    |||..||||..|..|:.|..:|:.||.||.|||:| :.|......|.
plant   261 NEPISKK---GLKKGEEQLRLVFSEFYQKLRRLKEYSFMNLLAFSKIMKKYEK-IASRNASRNYM 321

  Fly   176 KYVLKSTLAITLQLDRMISTTENMYTDYLANGDRSEAMAKLRVPPLGHPTPPVHVFSAGLFLG-- 238
            |.|..|.:..:.:::|::...|..:..:.::|:|.|.|..|| |.:......|..|| |.|.|
plant   322 KIVDNSLIGSSDEVNRLLERVEVTFVKHFSSGNRREGMKCLR-PKVKRERHRVTFFS-GFFSGCS 384

  Fly   239 LFLVSAILCFISYFAVDT--------SPEFRYTFVSLFRGPISGVTFGFCL------AINIKVYE 289
            :.||.|::     |.:::        ..|:....:.|:.      .|||.:      :.||..::
plant   385 IALVIAVV-----FKIESRKIMEKNYGTEYMANIIPLYS------LFGFIILHMLMYSANIYFWK 438

  Fly   290 TVGVNQVLIFEVERRNAIGAMRALEISSFFGYMCTLSILLYLL---------HKEFFIEDPIYIP 345
            ...||...||..::...:|......:|:....:..:..||.|.         ||..    |..||
plant   439 RYRVNYTFIFGFKQGTELGDREVFLVSTGLAVLAFVCFLLNLQLDMDWRMKHHKTL----PEVIP 499

  Fly   346 LVQVAFVVVLFLNPFRILFYSGRIWLLTVMGRILLSPFFFVNFADFWVADQWTSLVVTIVDHYYL 410
            |.....|:.:...||.|::.|.|.:.:..:...:.:|.:.|...||::.|..||.:..|......
plant   500 LCLATIVLFILFCPFNIIYRSSRFFFIRSLFHCICAPLYEVTLPDFFLGDHLTSQIQAIRSFELF 564

  Fly   411 VRFY-VRYFLDRS---------DAFEFEPDYAVAVIRCLPAWFRFAQSLRRFRDSGSKSTDYLIN 465
            :.:| :..:|.|.         :||.|       |:..:|.|.||.|.:||..:  .|.:.:..|
plant   565 ICYYGLGEYLQRQNKCHSHGVYNAFYF-------VVAVIPYWLRFLQCIRRLCE--EKESVHGYN 620

  Fly   466 ALKYFLFIAEVVFSTIQMETIAHYTDLFESPWTWAYITICIVSSIYT---VFWDLLMDFGLFRVW 527
            ||||.|.|..|:..|...         .:...||..:.: :.|.:.|   .|||:::|:||.|.
plant   621 ALKYMLTIIAVIVRTAYE---------LKKGRTWMILAL-VSSGVATGMNTFWDIVIDWGLLRK- 674

  Fly   528 NGENKFLRDNLVYPRWFYYF-VIVENTLLRCVW---ILEFALVHQELIAPYNGKSLICFSEIARR 588
            :.:|.:|||.|:.|....|| .:|.|.:||..|   :|||.|.....||.   .|:|...||.||
plant   675 HSKNPYLRDKLLVPHKSVYFAAMVVNVILRVAWMQLVLEFNLKSLHKIAV---TSIISCLEIIRR 736

  Fly   589 FFWNFLRLENEHLYNCGQFRATRDI 613
            ..|:|.|||||||.|.|::||.:.:
plant   737 GIWSFFRLENEHLNNVGKYRAFKSV 761

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10481	NP_995731.1	SPX_XPR1_like	2..163	CDD:269898	63/310 (20%)
		SPX	3..163	CDD:281146	62/309 (20%)
		EXS	267..601	CDD:281164	102/365 (28%)
AT1G69480	NP_001320450.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	174	1.000	Domainoid score	I1107
eggNOG	1	0.900	-	-		E1_COG5409
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	292	1.000	Inparanoid score	I823
OMA	1	1.010	-	-		QHG54286
OrthoDB	1	1.010	-	-		D536327at2759
OrthoFinder	1	1.000	-	-		FOG0000547
OrthoInspector	1	1.000	-	-		mtm1032
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10783
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X439
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.940