DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10481 and PHO1;H1

DIOPT Version :9

Sequence 1:	NP_995731.1	Gene:	CG10481 / 35273	FlyBaseID:	FBgn0032827	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_564940.1	Gene:	PHO1;H1 / 843205	AraportID:	AT1G68740	Length:	784	Species:	Arabidopsis thaliana

Alignment Length:	832	Identity:	199/832 - (23%)
Similarity:	317/832 - (38%)	Gaps:	259/832 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFGKTLDNLMVPEWRYQYMNYNELKQ------MIRNAVEK------------------------ 35
            :||.|..:..:||||:..:::|::||:      :..|.|||
plant     2 VKFTKQFEGQLVPEWKDAFVDYSQLKKDLKKIHLFTNGVEKKHTETSLIKTVKSSLGRLSIFGNK 66

  Fly    36 --------------APSGSRPSNDV-------AIGYYRNFEELFFNSCRVELTKVNYFFAHKQAE 79
                          |.|||  :|||       .|....:..:.||....::|.|||.|:..|:.|
plant    67 GREQSRVIQVHKKLASSGS--NNDVYETELLEKIADDTDAAKEFFACLDMQLNKVNQFYKTKEKE 129

  Fly    80 AHRKLATLNYQLD------------------RRRAQQDP-------------RGST--------- 104
            ...:...|..|:|                  .:.:::|.             ||.|
plant   130 FLERGECLKKQMDILIELKDAFKQKQANGESTQESKEDDSISCTISCEYDSVRGRTEEMQLQVSC 194

  Fly   105 ------------ASRGS------------------------------------------------ 109
                        .|.||
plant   195 LDNLEDNGEEALESLGSEEPIKANNEDSKLTTVSSRVFSCQGKNVKIKIPLTNPSRTFSAISYLI 259

  Fly   110 --ASSWSRQPEGKRKFPPIKK--------LRLAMSEFYLSLIMLQNYQTLNMTAFRKICKKYDKN 164
              :||....|:|..|....||        ::.|::|.:..|..|:.|:.||:.||..|.||:||
plant   260 NQSSSKKNGPDGGNKLQISKKKLSHAEKMIKGALTELFKGLNYLKTYRNLNILAFMNILKKFDK- 323

  Fly   165 LKSEAGFAWYEKYVLKSTLAITLQLDRMISTTENMYTDYLANGDRSEAMAKLRVPPLGHPTPPVH 229
            :..:.....|.|.|..|...|:.::..:....|..:..:||..:|.:||..|:    .|.....|
plant   324 VTGKQILPIYLKVVESSYFNISDKVMILSDEVEEWFIKHLAGENRRKAMKYLK----PHHRKESH 384

  Fly   230 --VFSAGLFLGLFLVSAILCFI--------------SYFAVDTSPEFRYTFVSLFRGPISGVTF- 277
              .|..|||.|.| |:.:..:|              :.|.::|:    |..:|:|     |:.|
plant   385 SVTFFIGLFTGCF-VALLAGYIIVAHLTGMYRQHSANTFYMETA----YPVLSMF-----GLLFL 439

  Fly   278 -GFCLAINIKVYETVGVNQVLIFEVERRNAIGAMRALEISSFFGYMCTLS---------ILLYLL 332
             .|....||.::....:|...|||      :|:...|:....| .:||.|         :.|.||
plant   440 HLFLYGCNIFMWRKARINYSFIFE------LGSKNELKYRDVF-LICTASMSAIAGVMFVHLSLL 497

  Fly   333 HKEFFIEDPIYIP-LVQVAFVVVLFLNPFRILFYSGRIWLLTVMGRILLSPFFFVNFADFWVADQ 396
            .|.:.......|| |:.:.|:::| :.|..|.:.|.|..|::|:..|:.||.:.|...||::|||
plant   498 EKGYSFRQVQVIPGLLLLGFLLIL-ICPLNIFYKSSRYRLISVIRNIVFSPLYKVVMLDFFMADQ 561

  Fly   397 WTSLVVTIVDHYYLVRFY---------------VRYFLDRSDAFEFEPDYAVAVIRCLPAWFRFA 446
            ..|.|..:.:..|:..:|               |:|:.|.:.|..|           ||.::|..
plant   562 LCSQVPMLRNLEYIACYYITGSYATQDYEYCMRVKYYRDLAYAVSF-----------LPYYWRAM 615

  Fly   447 QSLRRFRDSGSKSTDYLINALKYFLFIAEVVFSTIQMETIAHYTDLFESPWTWAYITICIVSSIY 511
            |..||:.|.|  .|.:|:|..||       |.:.:...|...|.......|....:.:..|::||
plant   616 QCARRWFDEG--ETSHLVNLGKY-------VSAMLAAGTKVAYEKERSLGWLCLVVAMSSVATIY 671

  Fly   512 TVFWDLLMDFGLFRVWNGENKFLRDNLVY-PRWFYYFVIVENTLLRCVW---ILEFALVHQELIA 572
            .::||.:.|:||.: .|..|.:||:.|:. .:..|||.:|.|.:||..|   :|..:..|.:
plant   672 QLYWDFVKDWGLLQ-HNSNNPWLRNQLMLRQKSIYYFSMVLNLVLRLAWLQTVLHSSFEHVD--- 732

  Fly   573 PYNGKSL-ICFSEIARRFFWNFLRLENEHLYNCGQFRATRDIFITRLDPQEE 623
             |....| :...|:.||..|||.|||||||.|.|:|||.:.:.:...:..||
plant   733 -YRVTGLFLAALEVIRRGQWNFYRLENEHLNNAGKFRAVKTVPLPFREVDEE 783

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10481	NP_995731.1	SPX_XPR1_like	2..163	CDD:269898	60/321 (19%)
		SPX	3..163	CDD:281146	59/320 (18%)
		EXS	267..601	CDD:281164	102/365 (28%)
PHO1;H1	NP_564940.1	SPX_PHO1_like	3..331	CDD:269897	62/330 (19%)
		SPX	4..336	CDD:281146	62/334 (19%)
		EXS	444..761	CDD:281164	98/349 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	174	1.000	Domainoid score	I1107
eggNOG	1	0.900	-	-		E1_COG5409
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	292	1.000	Inparanoid score	I823
OMA	1	1.010	-	-		QHG54286
OrthoDB	1	1.010	-	-		D536327at2759
OrthoFinder	1	1.000	-	-		FOG0000547
OrthoInspector	1	1.000	-	-		mtm1032
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10783
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X439
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.940