DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10481 and AT1G35350

DIOPT Version :9

Sequence 1:	NP_995731.1	Gene:	CG10481 / 35273	FlyBaseID:	FBgn0032827	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_174768.2	Gene:	AT1G35350 / 840424	AraportID:	AT1G35350	Length:	751	Species:	Arabidopsis thaliana

Alignment Length:	782	Identity:	207/782 - (26%)
Similarity:	327/782 - (41%)	Gaps:	191/782 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFGKTLDNLMVPEWRYQYMNYNELKQMIR------------NAVEKAPSGSRPSNDVAIGYYRN 53
            |||||.....|:|||:..||:|..||.::|            ..:::..||.|..:.:...|.|.
plant     1 MKFGKEYVAQMIPEWQQAYMDYTCLKTILREIKTSQKRSESQGVLKRKLSGRRNFSGLTKRYSRT 65

  Fly    54 F--------------------------------------EELFFNSCRVELTKVNYFFAHKQAEA 80
            |                                      |.:||.:..:|..|||.|:.....|.
plant    66 FSSRDLENHDIMVHATTGDDGFEKYETTILKVSEVGRESELVFFKTLDLEFDKVNRFYRSNVEEL 130

  Fly    81 HRKLATLNYQLDRRRA--------------------------QQDPRGST------------ASR 107
            .::...||.|:|...|                          .::.:|.|            .|.
plant   131 VKEAVVLNRQMDALIAYRIKLDQPSTSWSCSETVSVDINALDSKEQKGKTLAEEMGIKVEENVSN 195

  Fly   108 GSASSWSRQPE----------GKRKFPPIKKLR--LAMS------------------------EF 136
            |..|:....||          .|.:..|:..:|  |.:|                        ||
plant   196 GGDSTKETAPEALSVLDRIRLNKNQENPLSTIRNVLKLSNKEDIKFTKENLKKIEERLKNVFIEF 260

  Fly   137 YLSLIMLQNYQTLNMTAFRKICKKYDK-NLKSEAGFAWYEKYVLKSTLAITLQLDRMISTTENMY 200
            |..|..|:||..||..|..||.||||| .|::.|..  |.:.|.||.|..:.::::::...|:::
plant   261 YRKLRHLKNYSFLNTLAISKIMKKYDKIALRNAAKL--YMEMVDKSYLTSSDEINKLMLRVESIF 323

  Fly   201 TDYLANGDRSEAMAKLRVPPLGHPTPPVH--VFSAGLFLG--LFLVSAILCFISYFAVDTSPEFR 261
            .::.|..:||:.|..|| |.:   |...|  .||.|.|:|  :.||.|:..||....:..:...:
plant   324 VEHFAGSNRSKGMNLLR-PKV---TKEKHRITFSTGFFVGCTVSLVIALGLFIHARNIMGAVGHK 384

  Fly   262 YTFVSLFRGPISGVTFGFCL------AINIKVYETVGVNQVLIFEVERRNAIGAMRALEISSFFG 320
            ....::|  |:..: |.|.:      |.||..::...||...||..:....:|....|.:|  ||
plant   385 LYMETMF--PLYSL-FAFVVLHMIMYASNIYFWKRYRVNYPFIFGFKEGTELGYGHVLLLS--FG 444

  Fly   321 YMCTLSILLYLLHKEFFIEDP---------IYIPLVQVAFVVVLFLNPFRILFYSGRIWLLTVMG 376
             :.||::...|::.:..: ||         ..:||..||.|:.:.:.||.|.:.|.|.:.|.|:.
plant   445 -LGTLALCAVLVNMDMEM-DPNTNDYKTITELVPLFVVALVIAISVCPFNIFYRSSRFFFLMVLF 507

  Fly   377 RILLSPFFFVNFADFWVADQWTSLVVTIVDHYYLVRFYVRY-----FLDRSDAFEFEPDYAV--A 434
            |.:.:|.:.||..||::|||.||.|..:..    :.||:.|     |..|....:....|:.  .
plant   508 RCIAAPLYKVNLPDFFLADQLTSQVQALRS----LEFYICYYGWGDFKQRQSTCKSSDVYSTFYF 568

  Fly   435 VIRCLPAWFRFAQSLRRFRDSGSKSTDYLINALKYFLFIAEVVFSTIQMETIAHYTDLFESPWTW 499
            ::..:|.|.||.|.:||..:....|..:  |||||.|.|..|...|  ..:|....|...:.|.:
plant   569 IVAVIPYWSRFLQCVRRLIEEKDVSQGF--NALKYLLTIVAVCLRT--AFSINRGNDWKIAAWVF 629

  Fly   500 AYITICIVSSIYTVFWDLLMDFGLFRVWNGENKFLRDNLVYP-RWFYYFVIVENTLLRCVW---I 560
            :.:     ::.|..:||::.|:||..  .....:||:.|:.| :..||..:|.|.:||..|   :
plant   630 SGL-----ATFYGTYWDIVYDWGLLH--RPSKSWLREKLLVPHKSVYYVAMVVNVVLRLAWLQTV 687

  Fly   561 LEF--ALVHQELIAPYNGKSLICFSEIARRFFWNFLRLENEHLYNCGQFRATRDIFIT-RLDPQE 622
            |:|  :.:|:|.:.     :||...||.||..|||.|||||||.|.|:|||.:.:.:. ..|.:|
plant   688 LDFNISFLHRETMV-----ALIAILEIIRRGIWNFFRLENEHLNNVGKFRAFKSVPLPFNYDEEE 747

  Fly   623 ER 624
            :|
plant   748 DR 749

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10481	NP_995731.1	SPX_XPR1_like	2..163	CDD:269898	61/284 (21%)
		SPX	3..163	CDD:281146	60/283 (21%)
		EXS	267..601	CDD:281164	106/361 (29%)
AT1G35350	NP_174768.2	SPX_PHO1_like	2..295	CDD:269897	64/292 (22%)
		SPX	3..300	CDD:281146	65/298 (22%)
		EXS	391..725	CDD:281164	106/360 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	174	1.000	Domainoid score	I1107
eggNOG	1	0.900	-	-		E1_COG5409
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	292	1.000	Inparanoid score	I823
OMA	1	1.010	-	-		QHG54286
OrthoDB	1	1.010	-	-		D536327at2759
OrthoFinder	1	1.000	-	-		FOG0000547
OrthoInspector	1	1.000	-	-		mtm1032
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10783
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X439
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.940