DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10481 and AT1G26730

DIOPT Version :9

Sequence 1:	NP_995731.1	Gene:	CG10481 / 35273	FlyBaseID:	FBgn0032827	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_173995.1	Gene:	AT1G26730 / 839214	AraportID:	AT1G26730	Length:	750	Species:	Arabidopsis thaliana

Alignment Length:	775	Identity:	203/775 - (26%)
Similarity:	318/775 - (41%)	Gaps:	201/775 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFGKTLDNLMVPEWRYQYMNYNELKQMIR------------NAVEKAPSGSRPSNDVAIGYYR- 52
            |||||.....|:|||:..||:|..||.:::            ..:::..||||..:.:...|.|
plant     1 MKFGKDFVRQMIPEWQQAYMDYAGLKSILQEIQTSRKRSERPGILKRKLSGSRNFSGLTKRYSRT 65

  Fly    53 --------------------NFE----------------EL-FFNSCRVELTKVNYFFAHKQAEA 80
                                .||                || ||.:..:|..|||:|:..|..|.
plant    66 ASTREPEIQDILVHATTGDDGFERYETTILEVAEAGRESELAFFKTLDLEFDKVNHFYRSKVEEM 130

  Fly    81 HRKLATLNYQLDRRRA--------------------------QQDPRGSTA-----------SRG 108
            .::...||.|:|...|                          ..|.|.:.|           |.|
plant   131 VKEAVVLNKQMDALIAFRIKVERPSSSWSCSETVSVDMNALDSNDQRNTLAEEMGIRVEGNGSNG 195

  Fly   109 SASSWSRQPE----------GKRKFPPI--------------------------KKLRLAMSEFY 137
            ..|:....|:          .|.:..|:                          ::|:....|||
plant   196 GDSTKESVPQVLSVLERIRLNKTQETPLSTIKNVLKLSNQEELKFTRENLKKIEERLKNVFIEFY 260

  Fly   138 LSLIMLQNYQTLNMTAFRKICKKYDKNLKSEAGFAWYEKYVLKSTLAITLQLDRMISTTENMYTD 202
            ..|..|:||..||..|..||.||||| :.|.:....|.:.|.||.|..:.::::::...|:.:.:
plant   261 RKLRHLKNYSFLNTLAISKIMKKYDK-IASRSAAKPYMEMVDKSYLTSSDEINKLMLRVESTFVE 324

  Fly   203 YLANGDRSEAMAKLRVPPLGHPTPPVH------VFSAGLFLG--LFLVSAILCFISYFAVDTSPE 259
            :.|..:||:.|..||        |.|.      .||.|.|:|  :.||.|::.||....:..:..
plant   325 HFAGLNRSKGMNLLR--------PKVKKEKHRITFSTGFFVGCTVSLVVALVMFIHARNIMGAVG 381

  Fly   260 FRYTFVSLFRGPISGVTFGFCL------AINIKVYETVGVNQVLIFEVERRNAIGAMRALEISSF 318
            .:....::|  |:..: |.|.:      |.||..::...||...||..:....:|....|.:|
plant   382 HKVYMETMF--PLYSL-FAFVVLHMIMYASNIYFWKRYRVNYPFIFGFKEGTELGYRHVLLLS-- 441

  Fly   319 FGYMCTLSILLYLLHKEFFIEDP---------IYIPLVQVAFVVVLFLNPFRILFYSGRIWLLTV 374
            || :.||::...|::.:..: ||         ..:|:..:|.||.:...||.|.:.|.|::.|.|
plant   442 FG-LGTLALCAVLINLDMEM-DPNTNDYKTMTELLPMFILALVVAILFCPFNIFYRSSRVFFLMV 504

  Fly   375 MGRILLSPFFFVNFADFWVADQWTSLVVTIVDHYYLVRFYVRY-----FLDRSDAFEFEPDYAV- 433
            :.|.:.:|.:.||..||::|||.||.|..:..    :.||:.|     |..|.:.......|:.
plant   505 VFRCIAAPLYKVNLPDFFLADQLTSQVQALRS----LEFYICYYGWGDFKHRQNTCRSSDVYSTF 565

  Fly   434 -AVIRCLPAWFRFAQSLRRFRDSGSKSTDYLINALKYFLFIAEVVFSTIQMETIAHYTDLFESPW 497
             .::..:|.|.||.|.:||..:....|..|  |||||.|.:..|...|.       |:....:.|
plant   566 YFIVAVIPYWSRFLQCVRRLIEENDSSQGY--NALKYLLTVVAVCLRTA-------YSFNRGNIW 621

  Fly   498 ---TWAYITICIVSSIYTVFWDLLMDFGLFRVWNGENKFLRDNLVYP-RWFYYFVIVENTLLRCV 558
               .|.:..:   ::.|..:||::.|:||..  ......||:.|:.| :..||..||.|.:||..
plant   622 KISAWVFSAL---ATFYGTYWDIVFDWGLLH--RPSKHLLREKLLVPHKAVYYVAIVLNIVLRMA 681

  Fly   559 W---ILEFAL--VHQELIAPYNGKSLICFSEIARRFFWNFLRLENEHLYNCGQFRATRDI 613
            |   :|:|.|  :|:|.:.     :|:...||.||..|||.|||||||.|.|:|||.:.:
plant   682 WLQTVLDFNLSFLHRETMI-----ALLAALEIIRRGIWNFFRLENEHLNNVGKFRAFKSV 736

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10481	NP_995731.1	SPX_XPR1_like	2..163	CDD:269898	62/283 (22%)
		SPX	3..163	CDD:281146	61/282 (22%)
		EXS	267..601	CDD:281164	106/364 (29%)
AT1G26730	NP_173995.1	SPX_PHO1_like	2..294	CDD:269897	65/292 (22%)
		SPX	3..299	CDD:281146	65/296 (22%)
		SPX	<212..286	CDD:271919	18/73 (25%)
		EXS	390..724	CDD:281164	106/363 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	174	1.000	Domainoid score	I1107
eggNOG	1	0.900	-	-		E1_COG5409
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	292	1.000	Inparanoid score	I823
OMA	1	1.010	-	-		QHG54286
OrthoDB	1	1.010	-	-		D536327at2759
OrthoFinder	1	1.000	-	-		FOG0000547
OrthoInspector	1	1.000	-	-		mtm1032
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10783
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X439
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.940