DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10481 and AT1G14040

DIOPT Version :9

Sequence 1:	NP_995731.1	Gene:	CG10481 / 35273	FlyBaseID:	FBgn0032827	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_172857.2	Gene:	AT1G14040 / 837965	AraportID:	AT1G14040	Length:	813	Species:	Arabidopsis thaliana

Alignment Length:	837	Identity:	204/837 - (24%)
Similarity:	308/837 - (36%)	Gaps:	262/837 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFGKTLDNLMVPEWRYQYMNYNELKQMIRNAV------EKAPS--------------------- 38
            |||||...:.|||||:..||:|:.||.:::..:      ..|||
plant     1 MKFGKEFSSQMVPEWQQAYMDYDFLKTLLKEIITFKRRTNNAPSHGGAKTGGGLNRKLTLYRAFS 65

  Fly    39 ------------------------GSRPSNDVAI------GYYRNF----------EELFFNSCR 63
                                    ||..|..:.:      ||...|          |.:||....
plant    66 GLVSTPRHKRSNSSHDVEEGVQLTGSMRSGPILVNTTASHGYETTFLMAAEEGGEYELVFFRRLD 130

  Fly    64 VELTKVNYFFAHKQAEAHRKLATLNYQLDR----RRAQQDPRG---------------------- 102
            .|..||:.|:..|..|..::.|.||.|:|.    |...::|.|
plant   131 DEFNKVDKFYRKKVEEVLKEAAMLNKQMDALIAFRVKVENPDGWRWEERTVEMTRLASDIATSAA 195

  Fly   103 ---------------------------------------------------STASRGSASSWSRQ 116
                                                               ||.:..:.::.||.
plant   196 ALSASTPAGAKSMKVRSQEHMEAIQEGGSSRAGLMEDDEEDEDEQNETSVVSTGAIDNETTTSRM 260

  Fly   117 PEGKRKFP------------------PIK-----------------------KLRLAMSEFYLSL 140
             .|.|..|                  .||                       .|:.|..|||..|
plant   261 -RGARPSPIDVLGRVKINNTKETPRSTIKGVLKVSKQTDLKFSRENLMKVEESLKRAFIEFYQKL 324

  Fly   141 IMLQNYQTLNMTAFRKICKKYDKNLKSEAGFAWYEKYVLKSTLAITLQLDRMISTTENMYTDYLA 205
            .:|::|..||:.||.||.||||| :.|......|.|.|..|.|..:.::.|::...|..:..:.|
plant   325 RLLKSYSFLNVLAFSKILKKYDK-ITSRDATKPYMKVVDSSYLGSSDEVMRLMERVEATFIKHFA 388

  Fly   206 NGDRSEAMAKLRVPPLGHPTPPVHVFSAGLFLG--LFLVSAILCFI---SYFAVDTSPEFRYTFV 265
            |.:|::||..||  |..........||.|...|  ..|:.|::..|   :...::...|:..|..
plant   389 NANRAKAMNILR--PKAKRERHRITFSTGFSAGCVFSLIVALVAIIRTRNLLEMEGQKEYMNTMF 451

  Fly   266 SLFRGPISGVTFGFCL------AINIKVYETVGVNQVLIFEVERRNAIGAMRALEISSFFGYMCT 324
            .|:.      .|||.:      |.||..:....||...||..::...:|..:.|.:....|.:..
plant   452 PLYS------LFGFIVLHIIVYAANIYYWRRYRVNYSFIFGFKQGTELGYRQVLLVGFSIGVLAL 510

  Fly   325 LSILLYL------LHKEFFIEDPIYIPLVQVAFVVVLFLNPFRILFYSGRIWLLTVMGRILLSPF 383
            |.:|..|      ..|.:.....| :||:.:|.:.::.:.||...:.|.|.:.||.:...|.:|.
plant   511 LCVLANLDMEADPKTKAYQARTEI-LPLILLAAMFIVLVLPFNYFYRSSRFFFLTCLFHCLAAPL 574

  Fly   384 FFVNFADFWVADQWTSLVVTIVDHYYLVRFYVRYF-----------LDRSDAFE--FEPDYAVAV 435
            :.|...||::.||.||.|..|..    :.||:.|:           ...||.:.  |   :.|||
plant   575 YKVTLPDFFLGDQLTSQVQAIRS----IEFYICYYGWGDFRHRKSTCKESDVYNTFF---FIVAV 632

  Fly   436 IRCLPAWFRFAQSLRRFRDSGSKSTDYLINALKYFLFIAEVVFST---IQMETIAHYTDLFESPW 497
            |   |...|..|.|||..:..:....|  |.|||||.|..|...|   ||...:|         |
plant   633 I---PYVSRLLQCLRRLFEEKNPEQGY--NGLKYFLTIVAVCLRTAYSIQKGQVA---------W 683

  Fly   498 TWAYITICIVSSIYTVFWDLLMDFGLFRVWNGENKFLRDNLVYPRWFYYFV-IVENTLLRCVWI- 560
            .........:::|:..:||.:.|:||.. ...:|::|||.|:.|:...||: :|.|.|||..||
plant   684 RVLAAVFSFIAAIFCTYWDFVHDWGLLN-RTSKNRWLRDKLLVPQKKVYFIAMVLNVLLRFAWIQ 747

  Fly   561 ----LEFALVHQELIAPYNGKSLICFSEIARRFFWNFLRLENEHLYNCGQFRATRDI 613
                ..|:.:|::.:.     :::...||.||..|||.|||||||.|.|::||.:.:
plant   748 TVLDFNFSFMHRQTMV-----AIVASLEIIRRGIWNFFRLENEHLNNVGKYRAFKSV 799

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10481	NP_995731.1	SPX_XPR1_like	2..163	CDD:269898	66/345 (19%)
		SPX	3..163	CDD:281146	65/344 (19%)
		EXS	267..601	CDD:281164	104/367 (28%)
AT1G14040	NP_172857.2	SPX_PHO1_like	2..355	CDD:269897	69/354 (19%)
		SPX	3..360	CDD:281146	69/358 (19%)
		SPX	<284..347	CDD:271919	19/62 (31%)
		EXS	451..787	CDD:281164	104/369 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	174	1.000	Domainoid score	I1107
eggNOG	1	0.900	-	-		E1_COG5409
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	292	1.000	Inparanoid score	I823
OMA	1	1.010	-	-		QHG54286
OrthoDB	1	1.010	-	-		D536327at2759
OrthoFinder	1	1.000	-	-		FOG0000547
OrthoInspector	1	1.000	-	-		mtm1032
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10783
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X439
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.940