DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10481 and PHO1

DIOPT Version :9

Sequence 1:	NP_995731.1	Gene:	CG10481 / 35273	FlyBaseID:	FBgn0032827	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_188985.2	Gene:	PHO1 / 821924	AraportID:	AT3G23430	Length:	782	Species:	Arabidopsis thaliana

Alignment Length:	814	Identity:	195/814 - (23%)
Similarity:	316/814 - (38%)	Gaps:	233/814 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFGKTLDNLMVPEWRYQYMNYNELKQMIRNAVEKAPSGSRPSNDVAIGYYRNF----------- 54
            :||.|.|:..::|||:..::||..||:.|:..  |.....:|::...||::.:|
plant     2 VKFSKELEAQLIPEWKEAFVNYCLLKKQIKKI--KTSRKPKPASHYPIGHHSDFGRSLFDPVRKL 64

  Fly    55 -----EELFFNS-------------------------------------------CRV--ELTKV 69
                 ::||.||                                           .|:  ||.||
plant    65 ARTFSDKLFSNSEKPEILQVRRRRGSSETGDDVDEIYQTELVQLFSEEDEVKVFFARLDEELNKV 129

  Fly    70 NYFFAHKQAE----------------------AHRKLATLNYQLDRRRAQQDPRGSTASRGS--- 109
            |.|...|:.|                      :.||...|:.....|......|.|..|.||
plant   130 NQFHKPKETEFLERGEILKKQLETLAELKQILSDRKKRNLSGSNSHRSFSSSVRNSDFSAGSPGE 194

  Fly   110 ----ASSWSRQPE-----------------------GKRK------FPPI--------------- 126
                .|..||..|                       ||.|      .|..
plant   195 LSEIQSETSRTDEIIEALERNGVSFINSATRSKTKGGKPKMSLRVDIPDAVAGAEGGIARSIATA 259

  Fly   127 --------------------------KKLRLAMSEFYLSLIMLQNYQTLNMTAFRKICKKYDKNL 165
                                      ||:|.|..|.|..|.:|:.|.:|||.||.||.||:|| :
plant   260 MSVLWEELVNNPRSDFTNWKNIQSAEKKIRSAFVELYRGLGLLKTYSSLNMIAFTKIMKKFDK-V 323

  Fly   166 KSEAGFAWYEKYVLKSTLAITLQLDRMISTTENMYTDYLANGDRSEAMAKLRVPPLGHPTPPVHV 230
            ..:...:.|.|.|.:|....:.::.|::...|:::|.:.||.||.:||..|:    .|.|...|:
plant   324 AGQNASSTYLKVVKRSQFISSDKVVRLMDEVESIFTKHFANNDRKKAMKFLK----PHQTKDSHM 384

  Fly   231 --FSAGLFLGLFLVSAILCFISYFAVDTSPEFRYTFVSLFRG---------------PISGVTFG 278
              |..|||.|        ||||.|.:       |..::...|               |:..| |.
plant   385 VTFFVGLFTG--------CFISLFVI-------YIILAHLSGIFTSSDQVSYLETVYPVFSV-FA 433

  Fly   279 ------FCLAINIKVYETVGVNQVLIFEVERRNAIGAMRALEISSFFGYMCTLSILLYLLHKE-- 335
                  |....|:.:::...:|...|||.....|:....|..:.:.|......:::::|:.:.
plant   434 LLSLHMFMYGCNLYMWKNTRINYTFIFEFAPNTALRYRDAFLMGTTFMTSVVAAMVIHLILRASG 498

  Fly   336 FFIEDPIYIPLVQVAFVVVLFLNPFRILFYSGRIWLLTVMGRILLSPFFFVNFADFWVADQWTSL 400
            |.......||.:.:...:.:.:.||...:...|...:.::.:|:.|||:.|...||::.||.||
plant   499 FSASQVDTIPGILLLIFICVLICPFNTFYRPTRFCFIRILRKIVCSPFYKVLMVDFFMGDQLTS- 562

  Fly   401 VVTIVDH------YYLVRFYVRYFLDRSDAFEFEPDYAVAVIRCLPAWFRFAQSLRRFRDSGSKS 459
            .:.::.|      |:|.:.:..:..:......:..::|. :|..||.::|..|.:||:.|  ..:
plant   563 QIPLLRHLETTGCYFLAQSFKTHEYNTCKNGRYYREFAY-LISFLPYFWRAMQCVRRWWD--ESN 624

  Fly   460 TDYLINALKYFLFIAEVVFSTIQMETIAHYTDLFESPWTWAYITICIVSSIYTVFWDLLMDFGLF 524
            .|:|||..||   ::.:|.:.:::.......||    |....:...:|::||.::||.:.|:||.
plant   625 PDHLINMGKY---VSAMVAAGVRITYARENNDL----WLTMVLVSSVVATIYQLYWDFVKDWGLL 682

  Fly   525 RVWNGENKFLRDNLVY-PRWFYYFVIVENTLLRCVWILEFALVHQELIAPYNGKSLICF---SEI 585
            .. ..:|.:||||||. .:.|||..|..|.:||..||   ..:.:..::|.....|..|   .|:
plant   683 NP-KSKNPWLRDNLVLRNKNFYYLSIALNLVLRVAWI---ETIMRFRVSPVQSHLLDFFLASLEV 743

  Fly   586 ARRFFWNFLRLENEHLYNCGQFRATRDIFITRLD 619
            .||..|||.|:|||||.|.|||||.:.:.:..||
plant   744 IRRGHWNFYRVENEHLNNVGQFRAVKTVPLPFLD 777

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10481	NP_995731.1	SPX_XPR1_like	2..163	CDD:269898	65/320 (20%)
		SPX	3..163	CDD:281146	64/319 (20%)
		EXS	267..601	CDD:281164	90/366 (25%)
PHO1	NP_188985.2	SPX	2..336	CDD:397293	69/336 (21%)
PHO1	NP_188985.2	EXS	425..759	CDD:397303	89/349 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	174	1.000	Domainoid score	I1107
eggNOG	1	0.900	-	-		E1_COG5409
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	292	1.000	Inparanoid score	I823
OMA	1	1.010	-	-		QHG54286
OrthoDB	1	1.010	-	-		D536327at2759
OrthoFinder	1	1.000	-	-		FOG0000547
OrthoInspector	1	1.000	-	-		mtm1032
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10783
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X439
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.940