DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10481 and AT2G03260

DIOPT Version :9

Sequence 1:	NP_995731.1	Gene:	CG10481 / 35273	FlyBaseID:	FBgn0032827	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_178425.2	Gene:	AT2G03260 / 814855	AraportID:	AT2G03260	Length:	807	Species:	Arabidopsis thaliana

Alignment Length:	824	Identity:	207/824 - (25%)
Similarity:	329/824 - (39%)	Gaps:	242/824 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFGKTLDNLMVPEWRYQYMNYNELKQMIRNAVE---------------------------KAPS 38
            |||||.|.:.||.||:..|:||:.||.:::..::                           :|.|
plant     1 MKFGKELSSQMVQEWQQAYVNYDYLKTLLKEIIKLKEKTNPPPPPHHAVPGEGISRKMTLYRAFS 65

  Fly    39 G-----------SRPSN-----DVAIG----------------YYRNFEE------LFFNSCRVE 65
            |           ||.||     |:..|                :....||      :||.....|
plant    66 GLVQTPGKKRQSSRQSNYSSEIDIEEGKAPILVSKSTHGLETTFLMTAEEGGEYELVFFRRLDDE 130

  Fly    66 LTKVNYFFAHKQAEAHRKLATLNYQLDR----RRAQQDPRG-------------------STASR 107
            ..:|..|:..|..|..:....||.|:|.    |...::|.|                   |||:.
plant   131 FNRVEKFYKEKVEEVMKDAIMLNKQMDALIAFRVKVENPVGWGWEERTVEMTRLASDIATSTAAI 195

  Fly   108 GSAS---------------------SWSRQPE-----------------------GKRKFP---- 124
            .:::                     |:||:.|                       |.|..|
plant   196 AASTPARTRTMNPRAQAHMEAIQEGSFSRENEDEDHGSVRGATGDVKTSSLNTMRGARPAPIEVL 260

  Fly   125 --------------PIK-----------------------KLRLAMSEFYLSLIMLQNYQTLNMT 152
                          .||                       ||:.|..|||..|.:|::|..||:.
plant   261 DHIKINNTKATPRSTIKGVLNSSSQNEIIFNRQNLNEVEEKLKFAFVEFYQKLRLLKSYSFLNVL 325

  Fly   153 AFRKICKKYDKNLKSEAGFAWYEKYVLKSTLAITLQLDRMISTTENMYTDYLANGDRSEAMAKLR 217
            ||.||.||||| :.|......|.|.|..|.|..:.:|.::|...|:.:..:.|||.|.:.|..||
plant   326 AFSKILKKYDK-ITSRNASKSYMKMVDNSYLGSSDELMKLIQRVESTFIKHFANGHRRKGMNILR 389

  Fly   218 VPPLGHPTPPVHVFSAGLFLGLF--LVSAILCFISYFAVDTSPEFRY-TFV-SLFRGPISGVTFG 278
             |.:......| .||.|...|..  |:.|::..|.  ...|.||..: |:: ::|  |:..: ||
plant   390 -PQMKREKHRV-TFSTGFSAGCIFSLIVALVAIIR--TRKTMPEAEHNTYMNTMF--PLYSL-FG 447

  Fly   279 FCL------AINIKVYETVGVNQVLIFEVERRNAIGAMRALEISSFFGY-MCTLSILLYL--LHK 334
            |.:      ||:|..::...||...||..::...:|..:.|    |.|: :.|.::|..|  |..
plant   448 FIVLHITMYAIDIYYWKRYRVNYAFIFGCKQGTELGYRQVL----FLGFTIGTFALLCVLGNLDM 508

  Fly   335 EFFIEDPIYIPLVQ-------VAFVVVLFLNPFRILFYSGRIWLLTVMGRILLSPFFFVNFADFW 392
            |...:...:.||.:       ||..|||.: ||..|:.|.|.:.||.:...|.:|.:.|...||:
plant   509 EVNPKTKNFKPLTELLPLFLLVALFVVLIM-PFHFLYRSTRFFFLTCLLHCLAAPLYKVTLPDFF 572

  Fly   393 VADQWTSLVVTIVDHYYLVRFYVRY-----FLDRSDAFEFEP--DYAVAVIRCLPAWFRFAQSLR 450
            :.||.||.|..:..    :.||:.|     |..|.:..|...  .|::.::..||...|..|.:|
plant   573 LGDQLTSQVQALRS----INFYICYYGWGDFKKRQNTCEASEIYIYSLYIVASLPYLSRLLQCMR 633

  Fly   451 RFRDSGSKSTDYLINALKYFLFIAEVVFSTIQMETIAHYTDLFESPWTWAYITI-----CIVSSI 510
            |..:  .:|.|...|.:||.|.:..|...|      |:..::..:....:::.:     .|::::
plant   634 RMIE--ERSLDQGYNGVKYLLTVIAVSLRT------AYGYEVKNTKNPTSHLKVLAGSSSILAAV 690

  Fly   511 YTVFWDLLMDFGLFRVWNGENKFLRDNLVYPRWFYYFV-IVENTLLRCVWI-----LEFALVHQE 569
            :..:||.:.|:||... ..:|::|||.|:.|:...||: ::.|.:||..|:     .||..:|::
plant   691 FCTYWDFVHDWGLLNK-TSKNRWLRDKLLIPQKKVYFIAMILNVVLRFAWLQTILNFEFEFLHKQ 754

  Fly   570 LIAPYNGKSLICFSEIARRFFWNFLRLENEHLYNCGQFRATRDI 613
            ...     :::...||.||..|||.|:|||||.|.|:|||.:.:
plant   755 TTL-----AVVASLEIMRRGMWNFFRVENEHLNNVGKFRAFKSV 793

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10481	NP_995731.1	SPX_XPR1_like	2..163	CDD:269898	69/333 (21%)
		SPX	3..163	CDD:281146	68/332 (20%)
		EXS	267..601	CDD:281164	99/367 (27%)
AT2G03260	NP_178425.2	SPX_PHO1_like	2..344	CDD:269897	72/342 (21%)
		SPX	3..349	CDD:281146	72/346 (21%)
		EXS	440..781	CDD:281164	99/366 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	174	1.000	Domainoid score	I1107
eggNOG	1	0.900	-	-		E1_COG5409
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	292	1.000	Inparanoid score	I823
OMA	1	1.010	-	-		QHG54286
OrthoDB	1	1.010	-	-		D536327at2759
OrthoFinder	1	1.000	-	-		FOG0000547
OrthoInspector	1	1.000	-	-		mtm1032
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10783
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X439
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.940