Protein Alignment CdGAPr and RGA1

DIOPT Version :9

• Sequence 1: NP_001260600.1
• Gene: CdGAPr / 35267
• FlyBaseID: FBgn0032821
• Length: 1843
• Species: Drosophila melanogaster
• Sequence 2: NP_014770.1
• Gene: RGA1 / 854294
• SGDID: S000005653
• Length: 1007
• Species: Saccharomyces cerevisiae
• Alignment Length: 612
• Identity: 128/612 - (20%)
• Similarity: 228/612 - (37%)
• Gaps: 166/612 - (27%)

  Fly    65 NFKIVPADSLPGLSYQDMF--------------------------ASMNTSQISNAST------- 96
            |.|:.||..:.....||:.                          .|:|..:.::..|
Yeast   441 NVKLSPASKVTSRRSQDLMRDNDSHTGLDTPNSNSTSLDILVNNQKSLNYKRFTDNGTLRVTSGK 505

  Fly    97 ESSCSPPIQGAVPPPKPSRHM---AVQPLNSKSCRFPKLEECAHFHYERVQLGPLSVQLLDDKSE 158
            |::.......:...|.|..|:   ...|.|....|.|                ||...|..|:..
Yeast   506 ETALEEQKNHSFKSPSPIDHLLQSPATPSNVSMYRTP----------------PLDSSLTFDRRN 554

  Fly   159 HMGSSIASQSLG----GDLPHSSLRSFS--PESCWFIIRVCPQRCEPFLIKRSFENMQLLDEMLH 217
              |||.::|:..    ...|.:.|.:..  .|....:......|.:|.|.|........|.::
Yeast   555 --GSSYSNQNYSIPSWQKTPKTQLENSDNFEEQKETLYENSESRNDPSLDKEIVTAEHYLKQL-- 615

  Fly   218 RCVYDRKISGLRNM----EELAAELPSESDVEYAVAKYLERFSKIASDSLTCGTILTWLQLDNKG 278
                  ||: |:.:    |||..|:.....::.|:.:::|.:                   :::.
Yeast   616 ------KIN-LKELESQREELMKEITEMKSMKEALRRHIESY-------------------NSEK 654

  Fly   279 RRLPLADGETQRT---INTPAVGAAYGVRRYQAQAPDEINIEVGDMISVIDMPSPAESIWWR--- 337
            .:|.|...|....   ||..::|          ::|...::.....::    .|..:..:|:
Yeast   655 NKLYLDSNELSNNPPMINEISLG----------ESPPVKHVATASSVA----RSSVKPKFWKFFS 705

  Fly   338 GKKSHLQKSLYEVGFFPQSCVATIGDKVPRNFP--MPAPL----VGHLDASPTKPVLRKHG---- 392
            ..|...::|:       |.......:.:.::.|  :.||.    .|.|:.||  |||:...
Yeast   706 SAKPQTEQSI-------QGVSTNNTNSIVKSAPVLLSAPSSGSNSGRLEISP--PVLQNPNEFSD 761

  Fly   393 -KLIAFFRSFIL--SRPSRRRLKQSGIY-RERVFNCDLSEHLLNSGQDIPMVLRSCAEFIENYGV 453
             :|:.......:  |:.....|..|.:| ...|..|:...:      :|||:|..|.:|||:...
Yeast   762 VRLVPIENDANMGQSKDGEEYLDGSNLYGSSLVARCNYENN------EIPMILSVCIDFIESDEE 820

  Fly   454 ---IDGIYRLSGITSNIQRLRRAFDEERV---PDLGNPEMKQDIHAVSSLLKMYFRELPNPLCTY 512
               .:||||.||....|:.:.:.|...:|   .:..|...:||::.|:.:||.|.|:||||:.|:
Yeast   821 NMRSEGIYRKSGSQLVIEEIEKQFSAWKVQQNTETPNILTEQDLNVVTGVLKRYLRKLPNPIFTF 885

  Fly   513 QLYDNFVEAIQVK----------------ADEADERL---RLMKETVLKLPPPHYRTLKYLAEHL 558
            |:|:..:..::.|                |..:|..:   ..:|..:..||..|||.|:.|:||:
Yeast   886 QIYEPLMRLVKSKKMMENLPFVGGKLSLEAKNSDTYMSSKSALKNILEDLPREHYRVLRVLSEHI 950

  Fly   559 YKVSQHHGRTGMTDKNLAIVWAPNLLR 585
            .||:::.....||..|||:|:||.|:|
Yeast   951 EKVTRYSHWNRMTLYNLALVFAPGLIR 977

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CdGAPr	NP_001260600.1	PX_domain	168..274	CDD:295365	17/115 (15%)
		SH3_ARHGAP32_33	299..358	CDD:212769	6/61 (10%)
		RhoGAP_CdGAP	420..613	CDD:239849	59/191 (31%)
		FliJ	1322..1457	CDD:304890
RGA1	NP_014770.1	LIM1_Rga	13..67	CDD:188780
		LIM2_Rga	70..123	CDD:188781
		Smc	<569..>673	CDD:224117	21/131 (16%)
		RhoGAP	803..1002	CDD:214618	57/175 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	86	1.000	Domainoid score	I1869
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9247
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2255
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.940