Protein Alignment CdGAPr and RGA2

DIOPT Version :9

• Sequence 1: NP_001260600.1
• Gene: CdGAPr / 35267
• FlyBaseID: FBgn0032821
• Length: 1843
• Species: Drosophila melanogaster
• Sequence 2: NP_010667.1
• Gene: RGA2 / 851985
• SGDID: S000002787
• Length: 1009
• Species: Saccharomyces cerevisiae
• Alignment Length: 585
• Identity: 128/585 - (21%)
• Similarity: 238/585 - (40%)
• Gaps: 129/585 - (22%)

  Fly    73 SLPGLSYQDMFASMNTSQISNASTESSCSPPIQGAVPPPKPSRHMAV---QPLNSKSC-RFPKL- 132
            ::|..:::...:|:.:......|.:::.:..|.|:........|:|:   .||.|... :.|.|
Yeast   512 TVPEFNHKKAQSSLGSISKKQNSNDTATNRRINGSFTSSSSGHHIAMFRTPPLESGPLFKRPSLS 576

  Fly   133 EECAHFHYERVQLGPLSVQLLDDKSEHMGSSIAS-QSLGGD--LPHSSLRSFSPESCWFIIRVCP 194
            .|.||.....:|....:..||:|.|..:.::..| .||..|  ....:||....:     :|...
Yeast   577 SESAHHRSSSLQTSRSTNALLEDDSTKVDATDESATSLEKDFYFTELTLRKLKLD-----VRELE 636

  Fly   195 QRCEPFLIKRSFENMQLLDEMLHRCVYDRKISGLRNMEELAAELPSESDVEYAVAKYLERFSKIA 259
            ...:..|  :..||::|..|.|           |.:::.|..|...:|   .:..:.||:...||
Yeast   637 GTKKKLL--QDVENLRLAKERL-----------LNDVDNLTREKDKQS---ASSRESLEQKENIA 685

  Fly   260 SDSLTCGTILTWLQLDNKGRRLPLADGETQRTINTPAVGAAYGVRRYQAQAPDEINIEVGDMISV 324
            : |:|.              :.|.::.:.:.:|:..:....:.  :..:.|.|.   :|||:.|.
Yeast   686 T-SITV--------------KSPSSNSDRKGSISNASPKPRFW--KIFSSAKDH---QVGDLESQ 730

  Fly   325 IDMPSPAESIWWRGKKSHLQKSLYEVGFFPQSCVATIGDKVPRNFPMPAPLVGHLDASPTKPVLR 389
            ...|:.:..    |..:..||.:..    |:  :..:.|:      :|:|  |.:..||:
Yeast   731 QRSPNSSSG----GTTNIAQKEISS----PK--LIRVHDE------LPSP--GKVPLSPS----- 772

  Fly   390 KHGKLIAFFRSFILSRPSRRRLKQSGIYRERVFNCDLSEHLLNSGQDIPMVLRSCAEFIENYGV- 453
                            |.|......|   ..::...|..........:|:::|.|.:.||...:
Yeast   773 ----------------PKRLDYTPDG---SHLYGSSLQARCAYEKSTVPIIIRCCIDRIEKDDIG 818

  Fly   454 --IDGIYRLSGITSNIQRLRRAFDEER-------VPDLGNPEMKQDIHAVSSLLKMYFRELPNPL 509
              ::|:||.||..:.::.:...|.:..       .|.| |..:.||||||:|:||.|.|:||:|:
Yeast   819 LNMEGLYRKSGSQTLVEEIENEFAQNNSLHSDTLSPKL-NALLNQDIHAVASVLKRYLRKLPDPV 882

  Fly   510 CTYQLYDNFVEAIQVKADEADERLRL-------------MKETVLK--------LPPPHYRTLKY 553
            .::.:||..::.  |:.::..|||.|             :.|.|||        ||..|...||.
Yeast   883 LSFSIYDALIDL--VRNNQLIERLPLNNDKFLDSPQKVTIYEMVLKSLLEIFKILPVEHQEVLKV 945

  Fly   554 LAEHLYKVSQHHGRTGMTDKNLAIVWAPNLLRSPALESGGVAALRGVGVQAVVTEYLIRNCHNIF 618
            ||.|:.||.:...|..|...||::|:||:|:.    :..|...:..:..:..:.|:::.|..:||
Yeast   946 LAAHIGKVRRCSERNLMNLHNLSLVFAPSLIH----DFDGEKDIVDMKERNYIVEFILGNYRDIF 1006

  Fly   619  618
            Yeast  1007  1006

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CdGAPr	NP_001260600.1	PX_domain	168..274	CDD:295365	22/107 (21%)
		SH3_ARHGAP32_33	299..358	CDD:212769	11/58 (19%)
		RhoGAP_CdGAP	420..613	CDD:239849	60/223 (27%)
		FliJ	1322..1457	CDD:304890
RGA2	NP_010667.1	LIM1_Rga	13..67	CDD:188780
		LIM2_Rga	70..123	CDD:188781
		RhoGAP	815..1002	CDD:214618	54/193 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	86	1.000	Domainoid score	I1869
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9247
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000