DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CdGAPr and AT1G08340

DIOPT Version :9

Sequence 1:	NP_001260600.1	Gene:	CdGAPr / 35267	FlyBaseID:	FBgn0032821	Length:	1843	Species:	Drosophila melanogaster
Sequence 2:	NP_172310.1	Gene:	AT1G08340 / 837354	AraportID:	AT1G08340	Length:	331	Species:	Arabidopsis thaliana

Alignment Length:	266	Identity:	61/266 - (22%)
Similarity:	119/266 - (44%)	Gaps:	44/266 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   434 GQDIPMVLRSCAEFIENYGVI--DGIYRLSGITSNIQRLRRAFDEERVPDLGNPEMKQDIHAVSS 496
            |..:|::|......:.:.|.:  :|::|::|..|..:.:|...::..:||      ..|:|.::.
plant    61 GNCVPVILLLLQSRLYDQGGLQAEGVFRITGENSEEEFVREQLNKGIIPD------GIDVHCLAG 119

  Fly   497 LLKMYFRELP----NPLCTYQLYDNFVEAIQVKADEADER-LRLMKETVLKLPPPHYRTLKYLAE 556
            |:|.:|||||    :||.:.|:       :|.::||...: :||:.:|...|       |.:...
plant   120 LIKAWFRELPRGVLDPLPSEQV-------MQCESDEDFVKVVRLLPQTEASL-------LNWAIN 170

  Fly   557 HLYKVSQHHGRTGMTDKNLAIVWAPNLLRSPALESGGVAALRGVGVQAVVTEYLIRNCHNIFDAL 621
            .:..|.|......|..:|||:|:|||:.:.....:..:.|::.:.:...:||..:|
plant   171 LMADVIQFEHVNKMNSRNLALVFAPNMSQMADPLTALMYAVQVMKLLKSLTEKTVR--------- 226

  Fly   622 DDHPARHSMVASATAAAANAAGGELRLESLTDCESLLVEQREQDQSLGVVERPKSLSTGGAKLIS 686
             :..|..|:|  ....:..|..||...::..:.|....|:.|:|:     :..:.....|..:|.
plant   227 -EREASSSVV--DRRCSKEAEDGEKEKDNEEEEEDEEEEEEEEDE-----DEDEEEEGDGVYIIK 283

  Fly   687 LEEAQE 692
            .|||.|
plant   284 EEEASE 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CdGAPr	NP_001260600.1	PX_domain	168..274	CDD:295365
		SH3_ARHGAP32_33	299..358	CDD:212769
		RhoGAP_CdGAP	420..613	CDD:239849	44/185 (24%)
		FliJ	1322..1457	CDD:304890
AT1G08340	NP_172310.1	PBD	3..37	CDD:197628
AT1G08340	NP_172310.1	RhoGAP	65..217	CDD:238090	41/171 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910