DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CdGAPr and ROPGAP3

DIOPT Version :9

Sequence 1:	NP_001260600.1	Gene:	CdGAPr / 35267	FlyBaseID:	FBgn0032821	Length:	1843	Species:	Drosophila melanogaster
Sequence 2:	NP_850458.1	Gene:	ROPGAP3 / 819283	AraportID:	AT2G46710	Length:	455	Species:	Arabidopsis thaliana

Alignment Length:	419	Identity:	87/419 - (20%)
Similarity:	151/419 - (36%)	Gaps:	100/419 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   343 LQKSLYEVGFFPQSCVATIGDKVPRNFPMPAPLVGHLDAS-PTKPVLRKHGKLIAF--FRSFILS 404
            |:|||.      .||....|:.         .:|..:|.. ||:.   ||...:.|  |..| |.
plant    82 LRKSLV------MSCAMERGED---------DVVASMDIGWPTEV---KHVSHVTFDRFNGF-LG 127

  Fly   405 RPSR------RRLKQSGI----YRERVFNCDLSEHLLNSGQDIPMVLRSCAEFIENYGVI--DGI 457
            .||.      .|...:.:    ...:...|...:.    |..:|.:|....:.:...|.:  :||
plant   128 LPSELEPEVPPRAPSASVSVFGVSAKSMQCSYDDR----GNSVPTILLRMQKRLYTEGGLKAEGI 188

  Fly   458 YRLSGITSNIQRLRRAFDEERVPDLGNPEMKQDIHAVSSLLKMYFRELPNPLCTYQLYDNFVEAI 522
            :|::......:.:||..:...||      ...|:|.::.|:|.:|||||..:......:   :.:
plant   189 FRINPDNGKEEHVRRQLNCGVVP------RGIDVHCLAGLIKAWFRELPTGVLDVLTPE---QVM 244

  Fly   523 QVKADEADERLRLMKETVLKLPPPHYRTLKYLAEHLYKVSQHHGRTGMTDKNLAIVWAPNL--LR 585
            :...:|...||      |:.|||.....|.:....:..|.:|.....|..:|:|:|:|||:  :.
plant   245 RCNTEEDCSRL------VILLPPVESAILDWAIGLMADVVEHEQFNKMNARNVAMVFAPNMTQMA 303

  Fly   586 SPALESGGVAALRGVGVQAVVTEYLIRNC--------------HNIFDALDDHPARHSMVAS--- 633
            .|.     .|.:..|.|...:...::.|.              ....|..::..::||.:.|
plant   304 DPL-----TALIHAVQVMNFLKTLILMNLKERENADAKARWLKKQTSDPSEEWESQHSEILSPEK 363

  Fly   634 -----------ATAAAANAAGGE--LRLESLTDCESLLVEQREQDQSLGVVER-------PKSLS 678
                       ||.....|...|  ..::...|.|.:| :....:.::|.|:|       ..|.|
plant   364 PNNNNPKFLRVATLCRLEADNEEEFWNIKKRNDHEGVL-DTSSGNGNIGPVQRLCKHPLFQLSKS 427

  Fly   679 TGGAKLISLEEAQERHSRVEGADLKQSLP 707
            |..|.:.:.:|.  |..|...:....|||
plant   428 TKKAFVSNRDEG--RKGREAWSSRLSSLP 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CdGAPr	NP_001260600.1	PX_domain	168..274	CDD:295365
		SH3_ARHGAP32_33	299..358	CDD:212769	5/14 (36%)
		RhoGAP_CdGAP	420..613	CDD:239849	42/196 (21%)
		FliJ	1322..1457	CDD:304890
ROPGAP3	NP_850458.1	CRIB	103..143	CDD:238077	12/43 (28%)
ROPGAP3	NP_850458.1	RhoGAP	167..323	CDD:238090	40/175 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910