DRSC/TRiP Functional Genomics Resources

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Protein Alignment CdGAPr and Arhgap15

DIOPT Version :9

Sequence 1:NP_001260600.1 Gene:CdGAPr / 35267 FlyBaseID:FBgn0032821 Length:1843 Species:Drosophila melanogaster
Sequence 2:NP_722542.2 Gene:Arhgap15 / 76117 MGIID:1923367 Length:481 Species:Mus musculus


Alignment Length:430 Identity:114/430 - (26%)
Similarity:191/430 - (44%) Gaps:98/430 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   251 YLERFSKIA--SDSLTCGTILTWLQLDNKGRRLPLADGETQRTINTPAVGAAYGVRRYQAQAPDE 313
            ||:: :|||  ...|......:|:.|  .||::.......|:.:  |.:...:            
Mouse    93 YLQK-AKIADGGKKLRKNWSTSWIVL--SGRKIEFYKDSKQQAL--PNMKTRH------------ 140

  Fly   314 INIEVGDMISVIDMPSPAESIWWRGKKSHLQKSLYEV------GFFPQS-----------CVATI 361
             |:|..|:...        .|.|..:||. :||::::      .|..||           .:...
Mouse   141 -NVESVDLCGA--------HIEWAKEKSS-RKSVFQITTVSGNEFLLQSDIDFLILDWFQAIKNA 195

  Fly   362 GDKVPRNFPMPAPLVG-------------------HLDASPTKPVLRKHGKLIAF---------- 397
            .|::|:|     |..|                   |:|....||   :|.|...|          
Mouse   196 IDRLPKN-----PSCGSLELFNLQRSSSSELPSHCHIDRKEQKP---EHRKSFMFRLHHSASDTS 252

  Fly   398 --------FRSFILSRPSRRRLKQSGIYRERVFNCDLSEHLLNSGQDIPMVLRSCAEFIENYGV- 453
                    .:.||..|||.:.|::.|:.::::|...|..........:|..::.|.|.:|..|: 
Mouse   253 DKNRVKSRLKKFISRRPSLKTLQEKGLIKDQIFGSHLHTVCEREHSTVPWFVKQCIEAVEKRGLD 317

  Fly   454 IDGIYRLSGITSNIQRLRRAFDEERVPDLGNPEMKQDIHAVSSLLKMYFRELPNPLCTYQLYDNF 518
            :|||||:||..:.||:||...::|...:|.:.:. :|||.|:..|||:||||..||..|..::.|
Mouse   318 VDGIYRVSGNLATIQKLRFIVNQEEKLNLDDSQW-EDIHVVTGALKMFFRELSEPLFPYSFFERF 381

  Fly   519 VEAIQVKADEADERLRLMKETVLKLPPPHYRTLKYLAEHLYKVSQHHGRTGMTDKNLAIVWAPNL 583
            ||||  |..:::|::..|:..|.:||||::.|:|.|..||.|:.....:..|:.::|.||:.|.|
Mouse   382 VEAI--KKQDSNEKIETMRSLVKRLPPPNHDTMKILFRHLTKIVAKASQNLMSTQSLGIVFGPTL 444

  Fly   584 LRSPALESGGVAALRGVGVQAVVTEYLIRNCHNIFDALDD 623
            ||:.. |||.||.  .:..|..:.|:::.....||.:.:|
Mouse   445 LRAEN-ESGNVAV--HMVYQNQIAEFMLTEYDKIFSSEED 481

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CdGAPrNP_001260600.1 PX_domain 168..274 CDD:295365 7/24 (29%)
SH3_ARHGAP32_33 299..358 CDD:212769 12/75 (16%)
RhoGAP_CdGAP 420..613 CDD:239849 68/193 (35%)
FliJ 1322..1457 CDD:304890
Arhgap15NP_722542.2 PH 88..196 CDD:278594 24/129 (19%)
PH_ARHGAP9-like 89..198 CDD:270053 24/131 (18%)
RhoGAP_ARHGAP27_15_12_9 285..471 CDD:239868 68/191 (36%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1449
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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