Protein Alignment CdGAPr and arhgap27l

DIOPT Version :9

• Sequence 1: NP_001260600.1
• Gene: CdGAPr / 35267
• FlyBaseID: FBgn0032821
• Length: 1843
• Species: Drosophila melanogaster
• Sequence 2: XP_694888.4
• Gene: arhgap27l / 566523
• ZFINID: ZDB-GENE-120406-11
• Length: 1014
• Species: Danio rerio
• Alignment Length: 648
• Identity: 149/648 - (22%)
• Similarity: 235/648 - (36%)
• Gaps: 191/648 - (29%)

  Fly    39 STDKDAQAPPLQFEMDAP-----AAAISAQLNFKIVPAD-SLP---------------------- 75
            |.|||.:.||...|.|.|     .:.||.||     |.| .||
Zfish   436 SQDKDKERPPPLPEEDYPKNQHEESHISFQL-----PKDFQLPQIKRAVIPRAVMDTNKDVPTGW 495

  Fly    76 ----GLSYQDMFASMNTSQISNASTE------------SSCSPPI-QGAVPPPKPSRHMAVQ--- 120
                |...:.:|.|..|.:....|.:            |.|...: :.:|||.:|.....|:
Zfish   496 TQSVGTDGKSVFTSELTHEQWIQSKDEKGKLYYYSKDGSKCQWTLPEASVPPGQPMNGNGVEQDG 560

  Fly   121 PLNSKSCRFPKLEECAHFHYERVQLGPLSVQLLDDKSEHMGSSIASQSLGGDLPHSSLRSFSPES 185
            |....:.|:.:.    :...|.::..|...::..|.:....||       |:.|.|.
Zfish   561 PPVLNNWRYTQF----NISQEDLKFSPSHRRIASDNASDASSS-------GNSPESQ-------- 606

  Fly   186 CWFIIRVCPQRCEPFLIKRSFENMQLLDEMLHRCVYDRKISGLRNMEELAAELPSESDVEYAVAK 250
                                           |   ||:|....||:...:.:..|.
Zfish   607 -------------------------------H---YDKKFRRRRNLSSYSTDSHSH--------- 628

  Fly   251 YLERFSKIASDSLTCGTILTWLQLDNKGRRL---------PLADGETQRTINTPAVGAAYGVRRY 306
                     ..||....||...::...|:||         .|.||..  |.:.....|..|:...
Zfish   629 ---------HSSLEKAGILNKTKVAENGKRLRKNWAQSWTVLHDGVL--TFHKDPKFAPAGMSSK 682

  Fly   307 QAQAPDEINIEV-GDMISVIDMPSPAESIWWRGKKSHLQKSL----------YEVGFFPQSCVA- 359
            ..|...|..:|: |..:|            |..|:...:|::          |.:.:...|.:.
Zfish   683 TNQIVPEYTVELKGATLS------------WASKEKSSKKNVLELKTRHGSEYLIQYDTDSIIQD 735

  Fly   360 -------TI-------------GDKVPRNFPMPA-----PLVGHLDASPTKPVLRKHGKLIAFFR 399
                   ||             .:.||...|:||     |....|  |.|..:....|::....|
Zfish   736 WQKIILDTIKLLHEHGHNSEDEAEDVPEKSPLPADKEKKPEAARL--SSTSSIDTDQGRVRTKLR 798

  Fly   400 SFILSRPSRRRLKQSGIYRERVFNCDLSEHLLNSGQDIPMVLRSCAEFIENYGV-IDGIYRLSGI 463
            .|:..||:.:.:|:.|..:|.||.|.|..........:|..:..|...:|..|: ||||||:||.
Zfish   799 KFLQRRPTLQSVKEKGYIKENVFGCHLDTLCHRENTTVPKFVEKCIRSVEKRGLKIDGIYRVSGN 863

  Fly   464 TSNIQRLRRAFDEERVPDLGNPEMKQDIHAVSSLLKMYFRELPNPLCTYQLYDNFVEAIQVKADE 528
            .:.||:||...|.|...||.:.:. ::||.::..||::.||||.||..:..:|.|:.|||:  .:
Zfish   864 LAVIQKLRYKADHEEDLDLEDGQW-EEIHVITGALKLFLRELPEPLFPFSFFDKFIAAIQI--SD 925

  Fly   529 ADERLRLMKETVLKLPPPHYRTLKYLAEHLYKVSQHHGRTGMTDKNLAIVWAPNLLRSPALES 591
            ..:::..:::.|..||.|::.|::.|..||.||.:|.....|:.::.|||:.|.||| |..||
Zfish   926 YSQKVSYIRDLVRNLPLPNHDTMEVLFRHLRKVIEHGEMNRMSVQSTAIVFGPTLLR-PQEES 987

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CdGAPr	NP_001260600.1	PX_domain	168..274	CDD:295365	14/105 (13%)
		SH3_ARHGAP32_33	299..358	CDD:212769	12/69 (17%)
		RhoGAP_CdGAP	420..613	CDD:239849	61/173 (35%)
		FliJ	1322..1457	CDD:304890
arhgap27l	XP_694888.4	SH3_ARHGAP27	15..71	CDD:213002
		WW	340..368	CDD:278809
		WW	394..422	CDD:278809
		PH	632..745	CDD:278594	23/126 (18%)
		PH_ARHGAP9-like	633..744	CDD:270053	21/124 (17%)
		RhoGAP_ARHGAP27_15_12_9	821..1006	CDD:239868	60/171 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2255
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940