Protein Alignment CdGAPr and Arhgap25

DIOPT Version :9

• Sequence 1: NP_001260600.1
• Gene: CdGAPr / 35267
• FlyBaseID: FBgn0032821
• Length: 1843
• Species: Drosophila melanogaster
• Sequence 2: NP_001102717.1
• Gene: Arhgap25 / 500246
• RGDID: 1562105
• Length: 648
• Species: Rattus norvegicus
• Alignment Length: 639
• Identity: 154/639 - (24%)
• Similarity: 246/639 - (38%)
• Gaps: 179/639 - (28%)

  Fly   328 PSPAE---SIWWRGKKSHLQKS------------LY----EVGFFPQSCVATIGDKVPRNFPMPA 373
            |:|.|   .:.|..|:..:.|:            ||    |....||.|:.           :|.
  Rat    41 PNPLERPIKMGWLKKQRSIVKNWQQRYFVLKARQLYYYKDEEDSKPQGCMY-----------LPG 94

  Fly   374 PLVGHLDASPTKPVLRKHGKLIAFFR--------------SFILSRPSRRRLKQ--------SGI 416
            ..|..:..:|     .:.||.:  |.              |::|...|:..:::        :|.
  Rat    95 STVKEIATNP-----EEAGKFV--FEVIPASSDQNRTGQDSYVLMASSQVEMEEWVKFLRRVAGT 152

  Fly   417 YRERVFNCDLSE----------HLLNSGQDIPMVLRSCAEFIENYGVI-DGIYRLSGITSNIQRL 470
            ....||...|.|          ||      :|:::..|:|||..:||. :||:||.|..:.:::|
  Rat   153 PSGAVFGQRLDETVAYEQKFGPHL------VPILVEKCSEFILEHGVSEEGIFRLPGQDNLVKQL 211

  Fly   471 RRAFDEERVPDLGNPEMKQDIHAVSSLLKMYFRELPNPLCTYQLYDNFVEAIQV-KADEADERLR 534
            |.|||....|..   :...|:|.|:||||:|.|:||.|:..:..|:.|:...|: .||||..:..
  Rat   212 RDAFDAGERPSF---DRDTDVHTVASLLKLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQE 273

  Fly   535 LMKETVLKLPPPHYRTLKYLAEHLYKVSQHHGRTGMTDKNLAIVWAPNLLRS----PALESGGVA 595
            |.|:..: ||..:|..|.|:...|:::..:.....|:..|||.|...||:||    ||:
  Rat   274 LEKQLSI-LPRDNYNLLSYICRFLHEIQLNCAVNKMSVDNLATVIGVNLIRSKVEDPAV------ 331

  Fly   596 ALRGV-GVQAVVTEYLIRNCHNIF-----------------------------DALDDHPARHSM 630
            .:||. .:|.|:| .:||:...:|                             ||.:|.|...:.
  Rat   332 IMRGTPQIQRVMT-MMIRDHEVLFPKSKDAPLSPPAQKNDAKKAPVPRSSVGWDATEDPPLSRTD 395

  Fly   631 VASATAAAANAA--------------GGELRLESLTDCESLLVEQREQDQSLGVVERPKSLS--- 678
            ..:.||::.:|.              .|:...|:..|.:   ::.|::.|:|  ..|...|:
  Rat   396 SFNNTASSPDATSPTGPQPGDQHQEDSGKAPKENPGDWK---MQSRKRTQTL--PNRKCFLTSAF 455

  Fly   679 --TGGAKL----------ISLEEAQERHSRVEGADLKQSLPISMLTSASSNAASNIGSYIEVGGG 731
              |..:||          .|..:|.|.|.|....||:. |.....||...|..:...|.    |.
  Rat   456 QGTTSSKLEIFKNEFWSPSSEAKAGEGHRRTMSQDLRH-LSNDQRTSTYDNVPNPPVSQ----GN 515

  Fly   732 PSSLPDKYHTVLSAPRSWQKR-KPDKTPSWKSIFSRSQRQGNPDPGQKITTDVKDSVASRVSFVQ 795
            |:.       .||.|.|..|| .|..|.|.....|::..:.:||..|:....::..:.::....:
  Rat   516 PAG-------ELSPPASDSKRDAPVSTDSEMESGSKNSGEEDPDSLQRTVQHLQKEIEAQKQMYE 573

  Fly   796 ASHAHASKELTKHDK-PKSIELLETTSNERDPKPMDLCIRSNSIDSLRTVGHSR 848
            ....:..||  .:|. .|.:.|.|....|| .|...|.|      |||.|..||
  Rat   574 EQIKNLEKE--NYDVWAKVVRLNEELERER-KKFAALEI------SLRNVERSR 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CdGAPr	NP_001260600.1	PX_domain	168..274	CDD:295365
		SH3_ARHGAP32_33	299..358	CDD:212769	11/48 (23%)
		RhoGAP_CdGAP	420..613	CDD:239849	68/209 (33%)
		FliJ	1322..1457	CDD:304890
Arhgap25	NP_001102717.1	PH_RhoGap25-like	45..157	CDD:270083	20/129 (16%)
		PH	47..149	CDD:278594	18/119 (15%)
		RhoGAP_ARHGAP22_24_25	156..354	CDD:239855	69/214 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910