Protein Alignment CdGAPr and bcr

DIOPT Version :9

• Sequence 1: NP_001260600.1
• Gene: CdGAPr / 35267
• FlyBaseID: FBgn0032821
• Length: 1843
• Species: Drosophila melanogaster
• Sequence 2: NP_001123792.1
• Gene: bcr / 100170543
• XenbaseID: XB-GENE-980812
• Length: 1162
• Species: Xenopus tropicalis
• Alignment Length: 498
• Identity: 122/498 - (24%)
• Similarity: 198/498 - (39%)
• Gaps: 113/498 - (22%)

  Fly   142 RVQLGPLSVQLLDDKSEHMGSS-----------------IASQSLGGDLPHSSLRSFS------- 182
            :|::..|...:..:|..|.|..                 :.|.|:...:.:.:.:|::
 Frog   678 KVKISQLKSDIQREKKAHKGGKGLERLRKKLSEQESVLLLVSPSMAFRIQNRNGKSYTLLTWSDY 742

  Fly   183 PESCWF-IIRVCPQRCEPFLIKRSFENMQLLDEML-HRCVYDRKISGLRNMEELAAELPSESDVE 245
            ..:.|. .||...::|     .:||....|..:|| :.||      .|:.:..:...|..|.|..
 Frog   743 ERAEWAEHIREQQKKC-----FKSFSLSSLEIQMLTNSCV------KLQTVHRVPLTLSKEDDES 796

  Fly   246 YAVAKYLERFSKIASDSLTCGTILTWLQLDNKGRRLPLADGETQRTINTPAVGAAYGVRRYQAQA 310
            ..:..:|......|:.......:...|::|:.|..:..|.....|....|.....:
 Frog   797 SGLYGFLNVIVHSATGFQQSSNLFCTLEVDSFGYFVNKAKTRVYRNTTEPNWNEEF--------- 852

  Fly   311 PDEINIEVGDMISVIDMPSPAESIWWRGKKSHLQKSLYEVGFFPQSCVATIGDKVPRNFPMPAPL 375
              ||.:|....:.::...          |..:..:.:.|.|          ||...|   |.|..
 Frog   853 --EIELEGSQTLRILCYE----------KSCNRNRPMKEDG----------GDSSER---MVAKG 892

  Fly   376 VGHLDASPT------KPVLRKHG---KLIAFF--RSFILSR-PSRRRLKQSGIY---------RE 419
            ...|::...      :.|:..:|   ||...|  |.|.|.| |||   ||:|::         ||
 Frog   893 QVQLESQLALGKDWHRSVVSMNGIEVKLSMKFTSREFSLKRLPSR---KQTGVFGVKIAVVTKRE 954

  Fly   420 RVFNCDLSEHLLNSGQDIPMVLRSCAEFIENYGVID-GIYRLSGITSNIQRLRRAFDEERVPDLG 483
            |              ..:|.::|.|.|.||..|:.: ||||:||:.::||.|:.|||... .|:.
 Frog   955 R--------------SKVPYIVRQCVEEIERRGLEEVGIYRVSGVATDIQALKNAFDANN-KDVS 1004

  Fly   484 NPEMKQDIHAVSSLLKMYFRELPNPLCTYQLYDNFVEAIQVKADEADERLRLMKETVLKLPPPHY 548
            ......|::|::..||:||||||.||.|.:||.||.|.|.:....|.|  ..|...:|.||.|:.
 Frog  1005 VMMSDMDVNAIAGTLKLYFRELPAPLFTDELYPNFAEGIALSDPVAKE--SCMLNLLLSLPEPNL 1067

  Fly   549 RTLKYLAEHLYKVSQHHGRTGMTDKNLAIVWAPNLLRSPALES 591
            .|..:|.:||.:|:::..:..|:..|||.|:.|.|||....:|
 Frog  1068 LTFLFLLDHLKRVAENESQNKMSLHNLATVFGPTLLRPSEKDS 1110

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CdGAPr	NP_001260600.1	PX_domain	168..274	CDD:295365	20/114 (18%)
		SH3_ARHGAP32_33	299..358	CDD:212769	6/58 (10%)
		RhoGAP_CdGAP	420..613	CDD:239849	62/173 (36%)
		FliJ	1322..1457	CDD:304890
bcr	NP_001123792.1	Bcr-Abl_Oligo	3..73	CDD:312543
		SF-CC1	27..>149	CDD:273721
		RhoGEF	392..579	CDD:366202
		PH_BCR_vertebrate	574..767	CDD:270173	14/93 (15%)
		C2_ABR	803..924	CDD:176068	24/154 (16%)
		RhoGAP_Bcr	943..1143	CDD:239852	64/185 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2255
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030