Protein Alignment bsh and Nkx1-1

DIOPT Version :10

• Sequence 1: NP_477350.2
• Gene: bsh / 35266
• FlyBaseID: FBgn0000529
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_035450.1
• Gene: Nkx1-1 / 672284
• MGIID: 109346
• Length: 440
• Species: Mus musculus
• Alignment Length: 312
• Identity: 87/312 - (27%)
• Similarity: 116/312 - (37%)
• Gaps: 84/312 - (26%)

  Fly   102 PSQHSHPPQSHPPASASASATATARSNQAASGYAGEDYGKSMHSTPRSNHHSRHGTSHYNG---- 162
            |:.....|::.....|.::||..|.:..|....||:.|        |::....:|.|..:|
Mouse   124 PAASGRSPRAELERRALSAATGVAAAAGAEPTSAGDSY--------RADEAEANGYSSGSGRSPT 180

  Fly   163 ----DQISQQLGSGAAQHPPVPTTQPQPPPPPPLNGGSG--ASNGVLYPNAPYTDHGFLQMTLGY 221
                |:..:.  ....:.|.|...|....|    .||||  .:.|...|.|...:
Mouse   181 ADSEDEAPED--EDEEEAPEVQDAQGTEEP----RGGSGGLGARGSGCPGAAEVE---------- 229

  Fly   222 LSPSSGTYKSVDPYFLSQASLFGGAPFFGAPGCVPELALGLG------MGVNALRHCRR------ 274
            .||...|         :.....|.:|  |||| .|..|.|.|      .|.......:|
Mouse   230 ASPVDDT---------AAPGPRGNSP--GAPG-PPATATGAGSAGSTPQGAAVTTKPKRKRTGSD 282

  Fly   275 ------RKARTVFSDPQLSGLEKRFEGQRYLSTPERVELATALGLSETQVKTWFQNRRMKHKKQL 333
                  |:|||.|:..||..||.:|:..||||..||:.||.:|.|:|||||.||||||.|.|||
Mouse   283 SKSGKPRRARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQ- 346

  Fly   334 RRRDNANEPVDFSRSEPGKQPGEATSSSGDSKHGKLNPGS--VGG-TPTQPT 382
                           .||......|...|....| ..||:  .|| :|..|:
Mouse   347 ---------------NPGADTSAPTGGGGGPGPG-AGPGAGLPGGLSPLSPS 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsh	NP_477350.2	Homeodomain	275..331	CDD:459649	32/55 (58%)
Nkx1-1	NP_035450.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..82
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	145..291		37/181 (20%)
		Homeodomain	289..345	CDD:459649	32/55 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	342..387		15/58 (26%)