Protein Alignment bsh and NKX3-2

DIOPT Version :10

• Sequence 1: NP_477350.2
• Gene: bsh / 35266
• FlyBaseID: FBgn0000529
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_001180.1
• Gene: NKX3-2 / 579
• HGNCID: 951
• Length: 333
• Species: Homo sapiens
• Alignment Length: 396
• Identity: 104/396 - (26%)
• Similarity: 139/396 - (35%)
• Gaps: 130/396 - (32%)

  Fly    30 AMASATTMLTTKTPFSIEHILFQNLNSASNNNNSSDTNGIAANTNNYAPKSSRNAVKSA------ 88
            |:..|.|:    |.|||:.||          |...:..|:||.....||..:..:|.:|
Human     2 AVRGANTL----TSFSIQAIL----------NKKEERGGLAAPEGRPAPGGTAASVAAAPAVCCW 52

  Fly    89 -----RSAFAHDNNPHKHPSQHSHPPQSHPPASASASATATARSNQAASGYAGEDYGKSMHSTPR 148
                 |.|.|...            .:....||.:.:.||..|:.::..|:..:       |...
Human    53 RLFGERDAGALGG------------AEDSLLASPAGTRTAAGRTAESPEGWDSD-------SALS 98

  Fly   149 SNHHSRHGTSHYNGDQISQQLGSGAAQHPPVPTTQPQPPPPPPLNGGS----------GASNGVL 203
            ..:.||...:...|       .|||.                 |.|||          .||..:.
Human    99 EENESRRRCADARG-------ASGAG-----------------LAGGSLSLGQPVCELAASKDLE 139

  Fly   204 YPNAPYTDHGFLQMTLGYLSPSSGTYKSVDPYFLSQASLFGGAPFFGAPGCVPELALGLGMGV-- 266
            ...|..:|........|..||.:.. ..|.|.....::|..||.  |..|..|       .||
Human   140 EEAAGRSDSEMSASVSGDRSPRTED-DGVGPRGAHVSALCSGAG--GGGGSGP-------AGVAE 194

  Fly   267 ----NALRHCRRRKARTVFSDPQLSGLEKRFEGQRYLSTPERVELATALGLSETQVKTWFQNRRM 327
                .|....|::::|..||..|:..||:||..|||||.|||.:||.:|.|:|||||.||||||.
Human   195 EEEEPAAPKPRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRY 259

  Fly   328 KHKKQLRRRDNANEPVDFSRSEPGKQ----------------PGEATSSSGDSKHGKLNPGSVGG 376
            |.|    ||..|   .|...|.|..:                |||.           |.|.|:
Human   260 KTK----RRQMA---ADLLASAPAAKKVAVKVLVRDDQRQYLPGEV-----------LRPPSL-- 304

  Fly   377 TPTQPT 382
            .|.||:
Human   305 LPLQPS 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsh	NP_477350.2	Homeodomain	275..331	CDD:459649	32/55 (58%)
NKX3-2	NP_001180.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	65..113		10/73 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	138..212		18/83 (22%)
		Homeodomain	207..263	CDD:459649	33/59 (56%)