Protein Alignment bsh and NKX3-1

DIOPT Version :10

• Sequence 1: NP_477350.2
• Gene: bsh / 35266
• FlyBaseID: FBgn0000529
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_006158.2
• Gene: NKX3-1 / 4824
• HGNCID: 7838
• Length: 234
• Species: Homo sapiens
• Alignment Length: 262
• Identity: 68/262 - (25%)
• Similarity: 94/262 - (35%)
• Gaps: 79/262 - (30%)

  Fly   114 PASASASATATARSNQAASGYAGEDYGKSMHSTPRSNHHSRHGTSHYNGDQISQQLGSGAAQHPP 178
            |..|.|...|....::..:.:..:|.             .|.|.....|...||:      |..|
Human     9 PGEAKAEGAAPPTPSKPLTSFLIQDI-------------LRDGAQRQGGRTSSQR------QRDP 54

  Fly   179 VPTTQPQPPPPPPLNGG---SGASNGVLY--PNAPYTDHGFLQMTLGYLSPSSGTYKSVDPYFLS 238
            .|..:|:|      .||   :||.|..|.  |.|...:    ..||....|.    :.:..|.|.
Human    55 EPEPEPEP------EGGRSRAGAQNDQLSTGPRAAPEE----AETLAETEPE----RHLGSYLLD 105

  Fly   239 QASLFGGAPFFGAPGCVPELALGLGMGVNALRHCRRRKARTVFSDPQLSGLEKRFEGQRYLSTPE 303
            ..:..|..|........|:                 :::|..||..|:..||::|..|:|||.||
Human   106 SENTSGALPRLPQTPKQPQ-----------------KRSRAAFSHTQVIELERKFSHQKYLSAPE 153

  Fly   304 RVELATALGLSETQVKTWFQNRRMKHKKQLRRRDNANEPVDFSRSEPGKQPGEATSSSGD-SKHG 367
            |..||..|.|:|||||.||||||.|.|::                       :.:|..|| .||.
Human   154 RAHLAKNLKLTETQVKIWFQNRRYKTKRK-----------------------QLSSELGDLEKHS 195

  Fly   368 KL 369
            .|
Human   196 SL 197

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsh	NP_477350.2	Homeodomain	275..331	CDD:459649	30/55 (55%)
NKX3-1	NP_006158.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..131		32/171 (19%)
		Homeodomain	125..181	CDD:459649	30/55 (55%)