Protein Alignment bsh and MSX1

DIOPT Version :10

• Sequence 1: NP_477350.2
• Gene: bsh / 35266
• FlyBaseID: FBgn0000529
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_002439.2
• Gene: MSX1 / 4487
• HGNCID: 7391
• Length: 303
• Species: Homo sapiens
• Alignment Length: 304
• Identity: 84/304 - (27%)
• Similarity: 118/304 - (38%)
• Gaps: 49/304 - (16%)

  Fly   114 PASASASATATARSNQAASGYAGEDYGKSMHSTP---------RSNHHSRHGTSHYNGDQISQQL 169
            ||...|....:|.:..||:..|.|:..|...|..         .::|................|.
Human    24 PAGGGAGQAPSAAAATAAAMGADEEGAKPKVSPSLLPFSVEALMADHRKPGAKESALAPSEGVQA 88

  Fly   170 GSGAAQHPPVPTTQPQPPPPPPLNGGSGASNGVLYPNAPYTDHGFLQMTLGYL--SPSSGTYKSV 232
            ..|:|        ||...||    |..||      |:||.:.......::|.|  .|.....|:.
Human    89 AGGSA--------QPLGVPP----GSLGA------PDAPSSPRPLGHFSVGGLLKLPEDALVKAE 135

  Fly   233 DPYFLSQASLFGGAPFFGAPGCVPELALGLGMGVNALR-HCRRRKARTVFSDPQLSGLEKRFEGQ 296
            .|....:      .|:..:|...|..|..|......|| |...||.||.|:..||..||::|..:
Human   136 SPEKPER------TPWMQSPRFSPPPARRLSPPACTLRKHKTNRKPRTPFTTAQLLALERKFRQK 194

  Fly   297 RYLSTPERVELATALGLSETQVKTWFQNRRMKHKK----QLRRRDNANEPV----DFSRSEPGKQ 353
            :|||..||.|.:::|.|:|||||.||||||.|.|:    :|.:...|.:|:    .|..|.|...
Human   195 QYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPPAAFGLSFPLGG 259

  Fly   354 PGEATSSSGDSKHGKLNPGSVGGTPTQPTSEQQLQMCLMQQGYS 397
            |....:::|.|.:|...|......|..|..     :.....|||
Human   260 PAAVAAAAGASLYGASGPFQRAALPVAPVG-----LYTAHVGYS 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsh	NP_477350.2	Homeodomain	275..331	CDD:459649	30/55 (55%)
MSX1	NP_002439.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	18..55		9/30 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	69..117		14/65 (22%)
		PTZ00449	<105..>248	CDD:185628	51/154 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	133..174		10/46 (22%)
		Homeodomain	173..229	CDD:459649	30/55 (55%)