Protein Alignment bsh and DBX2

DIOPT Version :10

• Sequence 1: NP_477350.2
• Gene: bsh / 35266
• FlyBaseID: FBgn0000529
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_001004329.2
• Gene: DBX2 / 440097
• HGNCID: 33186
• Length: 339
• Species: Homo sapiens
• Alignment Length: 322
• Identity: 81/322 - (25%)
• Similarity: 115/322 - (35%)
• Gaps: 113/322 - (35%)

  Fly   102 PSQHSHPPQSHPPASASASATATARSNQAASGYAGEDYGKSMHSTPRSNHHSRHGTSHYNGDQIS 166
            |:....||..|.||:|.|:|.|..|...|:.        ..:...|.:...|..|..:  |.:.:
Human    50 PTPRLQPPAPHDPATALATAGAQLRPLPASP--------VPLKLCPAAEQVSPAGAPY--GTRWA 104

  Fly   167 QQLGSGAAQHPPVPTTQPQPPPPPPLNGGSGASNGVLYPNAPYTDHGFLQMTLGYLS-------- 223
            .|:.|.:|....:|...|            |..:....|:||.....||..|..:.|
Human   105 FQVLSPSADSARLPGRAP------------GDRDCTFQPSAPAPSKPFLLSTPPFYSACCGGSCR 157

  Fly   224 -PSSGT----YKSVDPYFLSQASLFGGAPFFGAPGCVPELALGLGMGVNALRHCRRRKA---RTV 280
             |:|.|    .:|:.| .|:|.|                             :.:.|:.   |.|
Human   158 RPASSTAFPREESMLP-LLTQDS-----------------------------NSKARRGILRRAV 192

  Fly   281 FSDPQLSGLEKRFEGQRYLSTPERVELATALGLSETQVKTWFQNRRM-----KHKKQL------- 333
            ||:.|...|||.|:.|:|:|..:|.:||..|||.|:|||.|||||||     |.|:.|
Human   193 FSEDQRKALEKMFQKQKYISKTDRKKLAINLGLKESQVKIWFQNRRMKWRNSKEKEVLSNRCIQE 257

  Fly   334 --------------------------------RRRDNANEPVD-FSRSEPGKQPGEATSSSG 362
                                            |.|:|:.||.: ..:...|..|.||.|..|
Human   258 VGLQEDPLSRSALGFPSPCPSIWDVPQQHSSPRWRENSPEPSERLIQESSGAPPPEANSLQG 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsh	NP_477350.2	Homeodomain	275..331	CDD:459649	31/63 (49%)
DBX2	NP_001004329.2	PRK12323	<3..>146	CDD:481241	28/117 (24%)
		Homeodomain	189..243	CDD:459649	29/53 (55%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	282..318		10/35 (29%)