Protein Alignment bsh and EVX2

DIOPT Version :10

• Sequence 1: NP_477350.2
• Gene: bsh / 35266
• FlyBaseID: FBgn0000529
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_001073927.1
• Gene: EVX2 / 344191
• HGNCID: 3507
• Length: 476
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 75/271 - (27%)
• Similarity: 105/271 - (38%)
• Gaps: 60/271 - (22%)

  Fly    77 APKSSRNAVKSARSAFAHDNNPHKHPSQHSHPPQSHPPASASASATATAR---------SNQAAS 132
            |.|...|...||.:|........:||::.|....|.|..||.....|..:         .:..:.
Human    21 AGKRFSNLSNSAGNAVLEALENSQHPARLSPRLPSAPLHSALGELPAKGKFEIDTLFNLQHTGSE 85

  Fly   133 GYAGEDYGKSMHSTPRSNHHSRHGTSHYNGDQISQ-QLGSGAAQHPPVPTTQPQPPPPPPLNGGS 196
            .....:...:..|..:..|:|....   ..|..|. ::|..|.:.|                ||.
Human    86 STVSSEISSAAESRKKPGHYSEAAA---EADMSSDVEVGCSALRSP----------------GGL 131

  Fly   197 GA-----SNGVLYPNAPYTDHGFLQMTLGYLSPSSGTYKSVDPYFLSQASLFGGAPFFGAPGCVP 256
            ||     :||     ..|.:.|   ...|..:.:||:         ...||.||:   |..|...
Human   132 GAAQLKENNG-----KGYAESG---SAAGTTTSASGS---------GLGSLHGGS---GGSGGSA 176

  Fly   257 ELALGLGMGVNALRHCRRRKARTVFSDPQLSGLEKRFEGQRYLSTPERVELATALGLSETQVKTW 321
            .|. |.|.|.:.:     |:.||.|:..|::.|||.|..:.|:|.|.|.|||.||.|.||.:|.|
Human   177 ALG-GSGSGADQV-----RRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVW 235

  Fly   322 FQNRRMKHKKQ 332
            |||||||.|:|
Human   236 FQNRRMKDKRQ 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsh	NP_477350.2	Homeodomain	275..331	CDD:459649	30/55 (55%)
EVX2	NP_001073927.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	82..113		3/33 (9%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	142..185		14/58 (24%)
		Homeodomain	189..245	CDD:459649	30/55 (55%)