Protein Alignment bsh and HOXD12

DIOPT Version :10

• Sequence 1: NP_477350.2
• Gene: bsh / 35266
• FlyBaseID: FBgn0000529
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_067016.3
• Gene: HOXD12 / 3238
• HGNCID: 5135
• Length: 270
• Species: Homo sapiens
• Alignment Length: 328
• Identity: 71/328 - (21%)
• Similarity: 101/328 - (30%)
• Gaps: 128/328 - (39%)

  Fly    20 ATTPTHSKAAAMASATTM-------LTTKTPFSIEHILFQNLNSASNNNNSSDTNGIAANTNNYA 77
            |.||.....|..|.||..       |....|..::              ..:..:|.......||
Human    52 AATPASCAPAQPAGATAFGGFSQPYLAGSGPLGLQ--------------PPTAKDGPEEQAKFYA 102

  Fly    78 PKSSRNAVKSARSAFAHDNNPHKHPSQHSHPPQSHPPASASASATATARSNQAASGYAGEDYGKS 142
            |:::..                  |.:......|..|.|:.|.|.|..::       |..||
Human   103 PEAAAG------------------PEERGRTRPSFAPESSLAPAVAALKA-------AKYDY--- 139

  Fly   143 MHSTPRSNHHSRHGTSHYNGDQISQQLGSGAAQHPPVPTTQPQPPPPPPLNGGSGASNGVLYPNA 207
                                        :|..:..|..||..|..|..|
Human   140 ----------------------------AGVGRATPGSTTLLQGAPCAP---------------- 160

  Fly   208 PYTDHGFLQMTLGYLS-----PSSGTYKSVDPYFLSQASLFGGAPFFGAPGCVPELALGLGMGVN 267
                 ||...|.|.|:     .::|....:.|      ||..|.|:..|||
Human   161 -----GFKDDTKGPLNLNMTVQAAGVASCLRP------SLPDGLPWGAAPG-------------- 200

  Fly   268 ALRHCRRRKARTVFSDPQLSGLEKRFEGQRYLSTPERVELATALGLSETQVKTWFQNRRMKHKKQ 332
                 |.||.|..::..|::.||..|....:::..:|.||:..|.||:.|||.||||||||.|:.
Human   201 -----RARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRV 260

  Fly   333 LRR 335
            :.|
Human   261 VLR 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsh	NP_477350.2	Homeodomain	275..331	CDD:459649	24/55 (44%)
HOXD12	NP_067016.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	102..122		4/37 (11%)
		Homeodomain	203..259	CDD:459649	24/55 (44%)