Protein Alignment bsh and HOXD4

DIOPT Version :10

• Sequence 1: NP_477350.2
• Gene: bsh / 35266
• FlyBaseID: FBgn0000529
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_055436.2
• Gene: HOXD4 / 3233
• HGNCID: 5138
• Length: 255
• Species: Homo sapiens
• Alignment Length: 241
• Identity: 68/241 - (28%)
• Similarity: 88/241 - (36%)
• Gaps: 62/241 - (25%)

  Fly   133 GYAGEDYGKSMHSTPRSNHHSRHG--TSHYNGDQISQQLGSGAAQHPPVPTTQPQPPPPPPLNGG 195
            |.:|...|.::   |...|....|  ..||            ||...|.|.  |..|||.||.|.
Human    63 GGSGPGPGSAL---PARGHGQEPGGPGGHY------------AAPGEPCPA--PPAPPPAPLPGA 110

  Fly   196 SGASNGVLYPNAPYTDHGFLQMTLGYLSPSSGTYKSVDPYFLSQASLFGGAPFFGAPGCVPELAL 260
            ...|..  .|..|.:.....|..:.|.........||:|.:.      ||.|
Human   111 RAYSQS--DPKQPPSGTALKQPAVVYPWMKKVHVNSVNPNYT------GGEP------------- 154

  Fly   261 GLGMGVNALRHCRRRKARTVFSDPQLSGLEKRFEGQRYLSTPERVELATALGLSETQVKTWFQNR 325
                          :::||.::..|:..|||.|...|||:...|:|:|..|.|||.|:|.|||||
Human   155 --------------KRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNR 205

  Fly   326 RMKHKKQLRRRDNANEPVDFSRSEPGKQPGEATSSSGDSKHGKLNP 371
            |||.||..:.      |....||.........:||...|:|  |.|
Human   206 RMKWKKDHKL------PNTKGRSSSSSSSSSCSSSVAPSQH--LQP 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsh	NP_477350.2	Homeodomain	275..331	CDD:459649	27/55 (49%)
HOXD4	NP_055436.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	31..127		22/82 (27%)
		Antp-type hexapeptide	133..138		1/4 (25%)
		Homeodomain	155..211	CDD:459649	27/55 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	212..255		9/40 (23%)