Protein Alignment bsh and HOXC13

DIOPT Version :10

• Sequence 1: NP_477350.2
• Gene: bsh / 35266
• FlyBaseID: FBgn0000529
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_059106.2
• Gene: HOXC13 / 3229
• HGNCID: 5125
• Length: 330
• Species: Homo sapiens
• Alignment Length: 285
• Identity: 72/285 - (25%)
• Similarity: 102/285 - (35%)
• Gaps: 87/285 - (30%)

  Fly   102 PSQH-----SHPPQSHPPASASA---------SATATAR----------SNQAASGYAGEDYGKS 142
            |:.|     .||....|||...|         .|...||          |:.|..|| |..:|.|
Human    65 PASHCRDLLPHPVLGRPPAPLGAPQGAVYTDIPAPEAARQCAPPPAPPTSSSATLGY-GYPFGGS 128

  Fly   143 MHSTPRSNHHSRHGTSHYNGDQISQQLG---SGAAQHPPVPTTQPQPPPPPPLNG---GSGASNG 201
                             |.|.::|..:.   ...|.||    ....|.|...|.|   .|.|...
Human   129 -----------------YYGCRLSHNVNLQQKPCAYHP----GDKYPEPSGALPGDDLSSRAKEF 172

  Fly   202 VLYPNAPYTDH---GFLQMTL-----GYLSPSSGTYKSVDPY-----------------FLSQAS 241
            ..||:...:..   |:|.:::     |:..|.......|:.|                 ..||::
Human   173 AFYPSFASSYQAMPGYLDVSVVPGISGHPEPRHDALIPVEGYQHWALSNGWDSQVYCSKEQSQSA 237

  Fly   242 LFGGAPFFGAPGCVPELALGLGMGVNALRHCRRRKARTVFSDPQLSGLEKRFEGQRYLSTPERVE 306
            ....:||   |..||     |...|::.|  |.||.|..::..||..|||.:...::::..:|..
Human   238 HLWKSPF---PDVVP-----LQPEVSSYR--RGRKKRVPYTKVQLKELEKEYAASKFITKEKRRR 292

  Fly   307 LATALGLSETQVKTWFQNRRMKHKK 331
            ::....|||.||..||||||:|.||
Human   293 ISATTNLSERQVTIWFQNRRVKEKK 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsh	NP_477350.2	Homeodomain	275..331	CDD:459649	21/55 (38%)
HOXC13	NP_059106.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..50
		HoxA13_N	54..168	CDD:463521	28/124 (23%)
		Homeodomain	261..312	CDD:459649	18/50 (36%)