Protein Alignment bsh and HOXC12

DIOPT Version :10

• Sequence 1: NP_477350.2
• Gene: bsh / 35266
• FlyBaseID: FBgn0000529
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_776272.1
• Gene: HOXC12 / 3228
• HGNCID: 5124
• Length: 282
• Species: Homo sapiens
• Alignment Length: 185
• Identity: 59/185 - (31%)
• Similarity: 78/185 - (42%)
• Gaps: 40/185 - (21%)

  Fly   170 GSGAAQHPPVPTTQPQPPPPPPL---------NGGSGASNGVLYPNAPYTDHGFLQMTLGYLSPS 225
            |.|||..|      .:|..||.|         .||.....|...|:.|               ||
Human   119 GPGAALLP------LEPSGPPALGFKYDYAAGGGGGDGGGGAGPPHDP---------------PS 162

  Fly   226 SGTYKS-VDPYFLSQASLFGGAPFFGAPG-CVPELALGLGMGVNALR----HCRRRKARTVFSDP 284
            ..:.:| .....|::.:...||   |.|| .|..|..|.|:..:...    :.|.||.|..:|..
Human   163 CQSLESDSSSSLLNEGNKGAGA---GDPGSLVSPLNPGGGLSASGAPWYPINSRSRKKRKPYSKL 224

  Fly   285 QLSGLEKRFEGQRYLSTPERVELATALGLSETQVKTWFQNRRMKHKKQLRRRDNA 339
            ||:.||..|....:::...|.||:..|.||:.|||.|||||||| ||:|..|:.|
Human   225 QLAELEGEFLVNEFITRQRRRELSDRLNLSDQQVKIWFQNRRMK-KKRLLLREQA 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsh	NP_477350.2	Homeodomain	275..331	CDD:459649	26/55 (47%)
HOXC12	NP_776272.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	94..129		5/15 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	147..214		17/84 (20%)
		Homeodomain	215..271	CDD:459649	27/56 (48%)