Protein Alignment bsh and HOXC5

DIOPT Version :10

• Sequence 1: NP_477350.2
• Gene: bsh / 35266
• FlyBaseID: FBgn0000529
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_061826.1
• Gene: HOXC5 / 3222
• HGNCID: 5127
• Length: 222
• Species: Homo sapiens
• Alignment Length: 301
• Identity: 68/301 - (22%)
• Similarity: 102/301 - (33%)
• Gaps: 120/301 - (39%)

  Fly    53 NLNSASNNNNSSDTNGIAANTNNY------------APKSSRNAVKSARSAFAHDNNPHKHPSQH 105
            |:.:..|..::|:   :.|:...|            ||.:|.:.|..|.       ||..||.:
Human    20 NMQTCGNYGSASE---VQASRYCYGGLDLSITFPPPAPSNSLHGVDMAA-------NPRAHPDR- 73

  Fly   106 SHPPQSHPPASASASATATARSNQAASGYA-GEDYGKSMHSTPRSNHHSRHGTSHYNGDQISQQL 169
                    ||.::|          ||.|:| |.|....::....|...:|....       .:..
Human    74 --------PACSAA----------AAPGHAPGRDEAAPLNPGMYSQKAARPALE-------ERAK 113

  Fly   170 GSGAAQHPPVPTTQP----QPPPPPPLNGGSGASNGVLYPNAPYTDHGFLQMTLGYLSPSSGTYK 230
            .||..:.....|.||    |||.||.           :||          .||..::|..:.
Human   114 SSGEIKEEQAQTGQPAGLSQPPAPPQ-----------IYP----------WMTKLHMSHETD--- 154

  Fly   231 SVDPYFLSQASLFGGAPFFGAPGCVPELALGLGMGVNALRHCRRRKARTVFSDPQLSGLEKRFEG 295
                                                       .:::||.::..|...|||.|..
Human   155 -------------------------------------------GKRSRTSYTRYQTLELEKEFHF 176

  Fly   296 QRYLSTPERVELATALGLSETQVKTWFQNRRMKHKKQLRRR 336
            .|||:...|:|:|..|.|:|.|:|.||||||||.||..:.:
Human   177 NRYLTRRRRIEIANNLCLNERQIKIWFQNRRMKWKKDSKMK 217

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsh	NP_477350.2	Homeodomain	275..331	CDD:459649	26/55 (47%)
HOXC5	NP_061826.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	68..141		23/109 (21%)
		Antp-type hexapeptide	140..145		2/14 (14%)
		Homeodomain	156..212	CDD:459649	26/55 (47%)