Protein Alignment bsh and HOXB5

DIOPT Version :10

• Sequence 1: NP_477350.2
• Gene: bsh / 35266
• FlyBaseID: FBgn0000529
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_002138.1
• Gene: HOXB5 / 3215
• HGNCID: 5116
• Length: 269
• Species: Homo sapiens
• Alignment Length: 277
• Identity: 76/277 - (27%)
• Similarity: 105/277 - (37%)
• Gaps: 81/277 - (29%)

  Fly   136 GEDY-------GKSM---HSTPRSNHHSRHGTSHYNGDQISQQLGSGAAQH----------PPVP 180
            |.||       |.|:   :..|.:.|...:| .:|||..:|....|.::.|          .|.|
Human    16 GPDYQLLNYGSGSSLSGSYRDPAAMHTGSYG-YNYNGMDLSVNRSSASSSHFGAVGESSRAFPAP 79

  Fly   181 TTQPQ------------PPPPPPLNGGS-GASNGVLYPNAPYTDHGFLQMTLGYLSPSSGTYKSV 232
            ..:|:            |...|..||.| ||......|:...|.           :.||..:..:
Human    80 AQEPRFRQAASSCSLSSPESLPCTNGDSHGAKPSASSPSDQATS-----------ASSSANFTEI 133

  Fly   233 DPYF-----------LSQASLFGGAP-----FFGAP-GCVPE-------LALGLGM-GVNALRHC 272
            |...           ||..||....|     ...|| |..|:       |.:...| |.:.
Human   134 DEASASSEPEEAASQLSSPSLARAQPEPMATSTAAPEGQTPQIFPWMRKLHISHDMTGPDG---- 194

  Fly   273 RRRKARTVFSDPQLSGLEKRFEGQRYLSTPERVELATALGLSETQVKTWFQNRRMKHKKQLRRRD 337
              ::|||.::..|...|||.|...|||:...|:|:|.||.|||.|:|.||||||||.||     |
Human   195 --KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK-----D 252

  Fly   338 NANEPVDFSRSEPGKQP 354
            |..:.:..:.:....||
Human   253 NKLKSMSLATAGSAFQP 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsh	NP_477350.2	Homeodomain	275..331	CDD:459649	29/55 (53%)
HOXB5	NP_002138.1	PRK07003	<67..>171	CDD:235906	22/114 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	77..173		23/106 (22%)
		Antp-type hexapeptide	176..181		0/4 (0%)
		Homeodomain	195..251	CDD:459649	29/55 (53%)