Protein Alignment bsh and HOXB4

DIOPT Version :10

• Sequence 1: NP_477350.2
• Gene: bsh / 35266
• FlyBaseID: FBgn0000529
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_076920.1
• Gene: HOXB4 / 3214
• HGNCID: 5115
• Length: 251
• Species: Homo sapiens
• Alignment Length: 295
• Identity: 79/295 - (26%)
• Similarity: 99/295 - (33%)
• Gaps: 121/295 - (41%)

  Fly   137 EDYGKSMHSTPRSNHHSRHGTSHYNGDQ-----ISQQLGSG----------AAQHPPVPTTQPQP 186
            |:|.:|.:..      |.|...:|.|.|     ...:.|.|          ||...|.|...|.|
Human    21 EEYSQSDYLP------SDHSPGYYAGGQRRESSFQPEAGFGRRAACTVQRYAACRDPGPPPPPPP 79

  Fly   187 PPPPPLNGGSGASNGVLYPNAPY-TDHGFLQMTLG--------------------YLSPSSGTYK 230
            |||||...|       |.|.||. ...|.|....|                    :.|||....|
Human    80 PPPPPPPPG-------LSPRAPAPPPAGALLPEPGQRCEAVSSSPPPPPCAQNPLHPSPSHSACK 137

  Fly   231 --------------SVDPYFLSQASLFGGAPFFGAPGCVPELALGLGMGVNALRHCRRRKARTVF 281
                          :|:|.:.      ||.|                           :::||.:
Human   138 EPVVYPWMRKVHVSTVNPNYA------GGEP---------------------------KRSRTAY 169

  Fly   282 SDPQLSGLEKRFEGQRYLSTPERVELATALGLSETQVKTWFQNRRMKHKKQLRRRDNANEPVDFS 346
            :..|:..|||.|...|||:...|||:|.||.|||.|:|.||||||||.||.
Human   170 TRQQVLELEKEFHYNRYLTRRRRVEIAHALCLSERQIKIWFQNRRMKWKKD-------------- 220

  Fly   347 RSEPGKQPGEATSSSGDSKHGKLNPGSVGGTPTQP 381
                .|.|.....|.|.:       ||.||.|.:|
Human   221 ----HKLPNTKIRSGGAA-------GSAGGPPGRP 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsh	NP_477350.2	Homeodomain	275..331	CDD:459649	29/55 (53%)
HOXB4	NP_076920.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..134		32/125 (26%)
		Antp-type hexapeptide	141..146		0/4 (0%)
		Homeodomain	163..219	CDD:459649	29/55 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	220..251		10/50 (20%)