Protein Alignment bsh and HOXA13

DIOPT Version :10

• Sequence 1: NP_477350.2
• Gene: bsh / 35266
• FlyBaseID: FBgn0000529
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_000513.2
• Gene: HOXA13 / 3209
• HGNCID: 5102
• Length: 388
• Species: Homo sapiens
• Alignment Length: 366
• Identity: 85/366 - (23%)
• Similarity: 136/366 - (37%)
• Gaps: 106/366 - (28%)

  Fly     3 MLNEASLSPADAHAHANA---TTPTHSKAAAMASATTMLTTKTPFSIEHILFQNLNSASNNNNSS 64
            |.:.|.|:|..|.|:::|   ..|:.:.|||.|:|..                   :|:...:||
Human    91 MAHPAPLAPGAASAYSSAPGEAPPSAAAAAAAAAAAA-------------------AAAAAASSS 136

  Fly    65 DTNGIAANTNNYAPKSSRNAVKSARSAFAHDNNPHKHPSQHSHP-----PQSHP--------PAS 116
            ...|.|......|.|.......:|:|:......|:.:.....:|     |  ||        |||
Human   137 GGPGPAGPAGAEAAKQCSPCSAAAQSSSGPAALPYGYFGSGYYPCARMGP--HPNAIKSCAQPAS 199

  Fly   117 ASASATATARSNQAASGYAGEDYGKSMHSTPRSNHHSRHGTSHYNGDQ----------ISQQLGS 171
            |:|:| |.|......:|.|.|::  |..:...:.:|..:....|:..|          :....|.
Human   200 AAAAA-AFADKYMDTAGPAAEEF--SSRAKEFAFYHQGYAAGPYHHHQPMPGYLDMPVVPGLGGP 261

  Fly   172 GAAQHPP--VPTTQPQPPPPPPLNGGSGASNGVLY-----PNAPYTDHGFLQMTLGYLSPSSGTY 229
            |.::|.|  :|....||...|  ||.    ||.:|     ...|:                  .:
Human   262 GESRHEPLGLPMESYQPWALP--NGW----NGQMYCPKEQAQPPH------------------LW 302

  Fly   230 KSVDPYFLSQASLFGGAPFFGAPGCVPELALGLGMGVNALRHCRRRKARTVFSDPQLSGLEKRFE 294
            ||..|..:|..|                         :|..:.|.||.|..::..||..||:.:.
Human   303 KSTLPDVVSHPS-------------------------DASSYRRGRKKRVPYTKVQLKELEREYA 342

  Fly   295 GQRYLSTPERVELATALGLSETQVKTWFQNRRMKHKKQLRR 335
            ..::::..:|..::....|||.||..||||||:|.||.:.:
Human   343 TNKFITKDKRRRISATTNLSERQVTIWFQNRRVKEKKVINK 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsh	NP_477350.2	Homeodomain	275..331	CDD:459649	20/55 (36%)
HOXA13	NP_000513.2	HoxA13_N	85..224	CDD:463521	39/156 (25%)
		Homeodomain	323..379	CDD:459649	20/55 (36%)