Protein Alignment bsh and HOXA4

DIOPT Version :10

• Sequence 1: NP_477350.2
• Gene: bsh / 35266
• FlyBaseID: FBgn0000529
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_002132.3
• Gene: HOXA4 / 3201
• HGNCID: 5105
• Length: 320
• Species: Homo sapiens
• Alignment Length: 304
• Identity: 84/304 - (27%)
• Similarity: 108/304 - (35%)
• Gaps: 88/304 - (28%)

  Fly   163 DQISQQLGSGAA----------QHPPVPTTQPQPPPPPPL-NGGSG-----------ASNGVLYP 205
            ::.:|..|||.|          |.||.|.||..|...|.| :.|.|           .:....||
Human    21 EEYAQHSGSGGADGGPGGGPGYQQPPAPPTQHLPLQQPQLPHAGGGREPTASYYAPRTAREPAYP 85

  Fly   206 NAP-YTDHGFLQMTLGY---------------------LSPSSGTYKS----------------- 231
            .|. |..||.......|                     ..|:.|.:.|
Human    86 AAALYPAHGAADTAYPYGYRGGASPGRPPQPEQPPAQAKGPAHGLHASHVLQPQLPPPLQPRAVP 150

  Fly   232 -VDPYFLSQASLFGGAPFFG-APGCVPELA----LGL------------GMGVNALRHC----RR 274
             ..|.....|....|.|..| ||.|...||    |||            .:.|:|:...    ..
Human   151 PAAPRRCEAAPATPGVPAGGSAPACPLLLADKSPLGLKGKEPVVYPWMKKIHVSAVNPSYNGGEP 215

  Fly   275 RKARTVFSDPQLSGLEKRFEGQRYLSTPERVELATALGLSETQVKTWFQNRRMKHKKQLRRRDNA 339
            :::||.::..|:..|||.|...|||:...|:|:|..|.|||.|||.||||||||.||. .:..|.
Human   216 KRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQVKIWFQNRRMKWKKD-HKLPNT 279

  Fly   340 NEPVDFSRSEPGKQPGEATSSSGDSKHGKLNPGSVGGTPTQPTS 383
            ......|.|.....||:|.:   .|.|...:|.....||. |:|
Human   280 KMRSSNSASASAGPPGKAQT---QSPHLHPHPHPSTSTPV-PSS 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsh	NP_477350.2	Homeodomain	275..331	CDD:459649	28/55 (51%)
HOXA4	NP_002132.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	19..77		16/55 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	101..168		7/66 (11%)
		Antp-type hexapeptide	194..199		0/4 (0%)
		Homeodomain	216..272	CDD:459649	28/55 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	273..320		13/52 (25%)