Protein Alignment bsh and HMX2

DIOPT Version :10

• Sequence 1: NP_477350.2
• Gene: bsh / 35266
• FlyBaseID: FBgn0000529
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_005510.1
• Gene: HMX2 / 3167
• HGNCID: 5018
• Length: 273
• Species: Homo sapiens
• Alignment Length: 235
• Identity: 72/235 - (30%)
• Similarity: 96/235 - (40%)
• Gaps: 59/235 - (25%)

  Fly   102 PSQHSHPPQSHPPASASASATATARSNQAASGYAGEDYGKSMHSTPRSNHHSRHGTSHYNGDQIS 166
            ||:....|...|....|.|  .::...:...|:          ..|......:||...
Human    30 PSEAPREPVGWPARKRSLS--VSSEEEEPDDGW----------KAPACFCPDQHGPKE------- 75

  Fly   167 QQLGSGAAQHPPVPTTQPQPPP---PPPLNGGSGASNGVLYPNAPYTDHGFLQMTLGYLSPSSGT 228
                .|...|||:|.      |   .|..:||||.              |.|:.| .:||||...
Human    76 ----QGPKHHPPIPF------PCLGTPKGSGGSGP--------------GGLERT-PFLSPSHSD 115

  Fly   229 YKSVDPYFLSQASLFGGAPFFGAPGCVPELALGLGMGVNALRHCRRRKARTVFSDPQLSGLEKRF 293
            :|..     .:..|..|:|   :||.......|......|    .::|.|||||..|:..||..|
Human   116 FKEE-----KERLLPAGSP---SPGSERPRDGGAERQAGA----AKKKTRTVFSRSQVYQLESTF 168

  Fly   294 EGQRYLSTPERVELATALGLSETQVKTWFQNRRMKHKKQL 333
            :.:||||:.||..||::|.|:||||||||||||.|.|:||
Human   169 DMKRYLSSSERACLASSLQLTETQVKTWFQNRRNKWKRQL 208

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsh	NP_477350.2	Homeodomain	275..331	CDD:459649	33/55 (60%)
HMX2	NP_005510.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..152		36/177 (20%)
		Homeodomain	150..206	CDD:459649	33/55 (60%)