Protein Alignment bsh and HLX

DIOPT Version :10

• Sequence 1: NP_477350.2
• Gene: bsh / 35266
• FlyBaseID: FBgn0000529
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_068777.1
• Gene: HLX / 3142
• HGNCID: 4978
• Length: 488
• Species: Homo sapiens
• Alignment Length: 371
• Identity: 99/371 - (26%)
• Similarity: 139/371 - (37%)
• Gaps: 132/371 - (35%)

  Fly   106 SHPPQSHPPASASASA------TATARSNQAASGYAGEDYGKSMHSTPRS-NHHSRHGTSHYNGD 163
            :|....||.||..|:|      |.....::..:|:       ....:|.| .:|      |::..
Human    74 AHLGSVHPHASFQAAARSPLRPTPVVAPSEVPAGF-------PQRLSPLSAAYH------HHHPQ 125

  Fly   164 QISQQLGSGAAQHPPVPTTQPQPPPPPPLNGG--SGASNGVLYPN------APYTDHGFLQ---- 216
            |..||      |.|     |.|.|||||..|.  ..||...:.||      ||......|:
Human   126 QQQQQ------QQP-----QQQQPPPPPRAGALQPPASGTRVVPNPHHSGSAPAPSSKDLKFGID 179

  Fly   217 -------------------------------MTLGYLSPSSGT-YKSVDPYFLSQASLFGGAPFF 249
                                           :.|..|.||:|. :.|:||...:.|.|   :|..
Human   180 RILSAEFDPKVKEGNTLRDLTSLLTGGRPAGVHLSGLQPSAGQFFASLDPINEASAIL---SPLN 241

  Fly   250 GAPGCVPELALGLGMGVNALRH-----------------------CRRRKARTVFSDPQLSGLEK 291
            ..|.             |:::|                       .:|..:|.|||:.|..||||
Human   242 SNPR-------------NSVQHQFQDTFPGPYAVLTKDTMPQTYKRKRSWSRAVFSNLQRKGLEK 293

  Fly   292 RFEGQRYLSTPERVELATALGLSETQVKTWFQNRRMK--HKKQLR-RRDNANE----------PV 343
            |||.|:|::.|:|.:||..|||::.|||.||||||||  |.|:.: ::|...|          ..
Human   294 RFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQAQKDKDKEAGEKPSGGAPAA 358

  Fly   344 DFSRSE--PGKQPGEATSSSGDSKHGKLNPGSVGGTPTQPTSEQQL 387
            |..:.|  |.:..|||.|.|.||:...:.|..   |.....||:.|
Human   359 DGEQDERSPSRSEGEAESESSDSESLDMAPSD---TERTEGSERSL 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsh	NP_477350.2	Homeodomain	275..331	CDD:459649	33/57 (58%)
HLX	NP_068777.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	118..173		21/71 (30%)
		Homeodomain	273..333	CDD:459649	33/59 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	331..488		19/74 (26%)