Protein Alignment bsh and Pdx1

DIOPT Version :10

• Sequence 1: NP_477350.2
• Gene: bsh / 35266
• FlyBaseID: FBgn0000529
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_074043.4
• Gene: Pdx1 / 29535
• RGDID: 62387
• Length: 283
• Species: Rattus norvegicus
• Alignment Length: 282
• Identity: 77/282 - (27%)
• Similarity: 102/282 - (36%)
• Gaps: 98/282 - (34%)

  Fly   173 AAQHPPVPT------------TQPQPPPPPPLNGGSGASNGVL----------YPNAPYTD---- 211
            |.|..|||.            .||.|||||...|    |.|.|          |...|..|
  Rat    19 AFQRGPVPEFSANPPACLYMGRQPPPPPPPQFAG----SLGTLEQGSPPDISPYEVPPLADDPAG 79

  Fly   212 ---HGFLQMTLGYLSPSSGTY----------------------KSVDPYFLSQASLFGGAPFFGA 251
               |..|...||...|..|.:                      ||...:  :..|.:.|    ||
  Rat    80 AHLHHHLPAQLGLAHPPPGPFPNGTETGGLEEPSRVHLPFPWMKSTKAH--AWKSQWAG----GA 138

  Fly   252 PGCVPELALGLGMGVNALRHCRRRKARTVFSDPQLSGLEKRFEGQRYLSTPERVELATALGLSET 316
            ....||               ..::.||.::..||..|||.|...:|:|.|.|||||..|.|:|.
  Rat   139 YAAEPE---------------ENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTER 188

  Fly   317 QVKTWFQNRRMKHKKQLRRRDNA---------NEPVDFSRSEPGKQ---------PGEATSSS-- 361
            .:|.||||||||.||:..::.::         .||........|::         ||.|..|.
  Rat   189 HIKIWFQNRRMKWKKEEDKKRSSGTTSGGGGGEEPEQDCAVTSGEELLALPPPPPPGGAVPSGVP 253

  Fly   362 GDSKHGKLNPGSVGGTPTQPTS 383
            ..::.|:| |..:..:| ||:|
  Rat   254 AAAREGRL-PSGLSASP-QPSS 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsh	NP_477350.2	Homeodomain	275..331	CDD:459649	28/55 (51%)
Pdx1	NP_074043.4	Transactivation domain	13..73		17/57 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	36..81		14/48 (29%)
		Antp-type hexapeptide	118..123		0/4 (0%)
		Homeodomain	147..203	CDD:459649	28/55 (51%)
		Nuclear localization signal. /evidence=ECO:0000250	197..203		4/5 (80%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	201..283		16/75 (21%)