DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bsh and VENTX

DIOPT Version :9

Sequence 1:	NP_477350.2	Gene:	bsh / 35266	FlyBaseID:	FBgn0000529	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_055283.1	Gene:	VENTX / 27287	HGNCID:	13639	Length:	258	Species:	Homo sapiens

Alignment Length:	204	Identity:	62/204 - (30%)
Similarity:	83/204 - (40%)	Gaps:	53/204 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   163 DQISQQLGSGAAQHPPVPTTQPQPPPPPPLNGGSGASNGVLYPNAPYTDHGFLQMTLGYL---SP 224
            |.:||...||       ||..|:|                            ...:||.|   ..
Human    21 DWLSQSSCSG-------PTHTPRP----------------------------ADFSLGSLPGPGQ 50

  Fly   225 SSGTYKSVDPYFLSQASLFGGAPFFGAPGCVPELAL-GLGMGVNALRHCRRRKARTVFSDPQLSG 288
            :||..:......:.:|:.....|       .||..: ||....|.||..|   .||.|:..|:..
Human    51 TSGAREPPQAVSIKEAAGSSNLP-------APERTMAGLSKEPNTLRAPR---VRTAFTMEQVRT 105

  Fly   289 LEKRFEGQRYLSTPERVELATALGLSETQVKTWFQNRRMKHKKQLRRRDNANEPVDFSRSEPGKQ 353
            ||..|:..:|||..||..||..:.|||.|:||||||||||||:|: :....:.|...|...|
Human   106 LEGVFQHHQYLSPLERKRLAREMQLSEVQIKTWFQNRRMKHKRQM-QDPQLHSPFSGSLHAP--- 166

  Fly   354 PGEATSSSG 362
            |...::|||
Human   167 PAFYSTSSG 175

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bsh	NP_477350.2	Homeobox	278..330	CDD:278475	28/51 (55%)
VENTX	NP_055283.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..93		23/113 (20%)
		Homeobox	95..147	CDD:306543	28/51 (55%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	227..248
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR24327
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010