Protein Alignment bsh and GBX1

DIOPT Version :10

• Sequence 1: NP_477350.2
• Gene: bsh / 35266
• FlyBaseID: FBgn0000529
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_001092304.1
• Gene: GBX1 / 2636
• HGNCID: 4185
• Length: 363
• Species: Homo sapiens
• Alignment Length: 317
• Identity: 93/317 - (29%)
• Similarity: 126/317 - (39%)
• Gaps: 93/317 - (29%)

  Fly    66 TNGIAANTNNYAPKSSRNAVKSARSAFAHDNNPHKHPSQHSHPPQSHPPASASASATATARSNQA 130
            ||...|......|  |..|:.:|..:||       .|....:.||....|:|:|:||| ||:|..
Human    84 TNTFCAGLGQAVP--SMVALTTALPSFA-------EPPDAFYGPQELAAAAAAAAATA-ARNNPE 138

  Fly   131 ASGYAGEDYGKSMHSTPRSNHHSRHGTSHYNGDQISQQLGSGAAQHPPVPTTQPQPPPPPPLNGG 195
            ..|...|.                               |..|.:..|......:||||||.:..
Human   139 PGGRRPEG-------------------------------GLEADELLPAREKVAEPPPPPPPHFS 172

  Fly   196 SGASNGVLYPNAP------YTDHGFLQMTLGYLSPSSGTYK-------SVDPYFLSQASLFGGAP 247
            .      .:|:.|      .:|...|:.:.|  .|:....:       |.|..||..::
Human   173 E------TFPSLPAEGKVYSSDEEKLEASAG--DPAGSEQEEEGSGGDSEDDGFLDSSA------ 223

  Fly   248 FFGAPGCV----PEL--ALGLG--------MGVNALRHCRRRKARTVFSDPQLSGLEKRFEGQRY 298
              |.||.:    |:|  :||.|        .||.|.....||: ||.|:..||..|||.|..::|
Human   224 --GGPGALLGPKPKLKGSLGTGAEEGAPVTAGVTAPGGKSRRR-RTAFTSEQLLELEKEFHCKKY 285

  Fly   299 LSTPERVELATALGLSETQVKTWFQNRRMKHKKQLRRRDNANEPVDFSRS-EPGKQP 354
            ||..||.::|.||.|||.|||.||||||.|.|:  .:..|.:     ||| ||.:.|
Human   286 LSLTERSQIAHALKLSEVQVKIWFQNRRAKWKR--IKAGNVS-----SRSGEPVRNP 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsh	NP_477350.2	Homeodomain	275..331	CDD:459649	31/55 (56%)
GBX1	NP_001092304.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..31
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	128..265		41/185 (22%)
		Homeodomain	262..318	CDD:459649	32/56 (57%)