Protein Alignment bsh and NKX2-8

DIOPT Version :10

• Sequence 1: NP_477350.2
• Gene: bsh / 35266
• FlyBaseID: FBgn0000529
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_055175.2
• Gene: NKX2-8 / 26257
• HGNCID: 16364
• Length: 239
• Species: Homo sapiens
• Alignment Length: 240
• Identity: 69/240 - (28%)
• Similarity: 89/240 - (37%)
• Gaps: 77/240 - (32%)

  Fly   174 AQHPPVPTTQPQPPPPPPLNGGSGASNGVLYPNAPYTDHGFLQMTLGYLSPSSGTYKSVDPYFLS 238
            |||.|....:|:.|.|.|......:..|    :.|.:|...|:.:    .|.|....|..|
Human    22 AQHLPRREPEPRAPQPDPCAAWLDSERG----HYPSSDESSLETS----PPDSSQRPSARP---- 74

  Fly   239 QASLFGGAPFFGAPGCVPELALGLGMGVNALRHCRRRKARTVFSDPQLSGLEKRFEGQRYLSTPE 303
                       .:||...|               :|:|.|.:||..|...||:||..|||||.||
Human    75 -----------ASPGSDAE---------------KRKKRRVLFSKAQTLELERRFRQQRYLSAPE 113

  Fly   304 RVELATALGLSETQVKTWFQNRRMKHKKQLRRRDNANEPVDFSRS-----EPG------------ 351
            |.:||:.|.|:.||||.||||.|.|.|:  .|...|.|..|.:.|     .||
Human   114 REQLASLLRLTPTQVKIWFQNHRYKLKR--ARAPGAAESPDLAASAELHAAPGLLRRVVVPVLVR 176

  Fly   352 -KQP------GEATSSSGDSKHG-------------KLNPGSVGG 376
             .||      ||..:::...|.|             ...|||..|
Human   177 DGQPCGGGGGGEVGTAAAQEKCGAPPAAACPLPGYPAFGPGSALG 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsh	NP_477350.2	Homeodomain	275..331	CDD:459649	31/55 (56%)
NKX2-8	NP_055175.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..87		20/102 (20%)
		Homeodomain	85..141	CDD:459649	31/55 (56%)