Protein Alignment bsh and Tlx2

DIOPT Version :10

• Sequence 1: NP_477350.2
• Gene: bsh / 35266
• FlyBaseID: FBgn0000529
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_033418.1
• Gene: Tlx2 / 21909
• MGIID: 1350935
• Length: 284
• Species: Mus musculus
• Alignment Length: 263
• Identity: 78/263 - (29%)
• Similarity: 101/263 - (38%)
• Gaps: 87/263 - (33%)

  Fly    98 PHKHPSQHS--------HPP----------QSHPPASASASATATARSNQAASGYAGEDYGKSMH 144
            ||..|....        .||          |||..::|.:|..      ..|||||.   ..|:.
Mouse    12 PHHEPISFGIDQILSGPEPPGGGLGPGQSGQSHGESAAFSSGF------HGASGYAP---AGSLA 67

  Fly   145 STPRSNHHSRHGTSHYNGDQISQQLGSGAAQHPPVPTTQPQPPPPP-------PLNGGSGASNGV 202
            |.||.:                   |.|......||..:|.|.|||       |...|.|.:.|:
Mouse    68 SLPRGS-------------------GVGPGGVIRVPAHRPLPVPPPSGAAPAVPGPSGLGGAGGL 113

  Fly   203 LYPNAPYTDHG--FLQMTL-GYLSPSSGTYKSVDPYFLSQASLFGGAPFFGAPGCVPELALGLGM 264
            .....|:.|.|  |.:..| ..|||.|||.:...||                ....|.
Mouse   114 AGLTFPWMDSGRRFAKDRLTAALSPFSGTRRIGHPY----------------QNRTPP------- 155

  Fly   265 GVNALRHCRRRKARTVFSDPQLSGLEKRFEGQRYLSTPERVELATALGLSETQVKTWFQNRRMKH 329
                    :|:|.||.||..|:..||:||..|:||::.||..||.||.:::.||||||||||.|.
Mouse   156 --------KRKKPRTSFSRSQVLELERRFLRQKYLASAERAALAKALRMTDAQVKTWFQNRRTKW 212

  Fly   330 KKQ 332
            ::|
Mouse   213 RRQ 215

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsh	NP_477350.2	Homeodomain	275..331	CDD:459649	30/55 (55%)
Tlx2	NP_033418.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..52		6/31 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	78..104		8/25 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	140..166		11/56 (20%)
		Homeodomain	158..214	CDD:459649	30/55 (55%)