Protein Alignment bsh and EMX1

DIOPT Version :10

• Sequence 1: NP_477350.2
• Gene: bsh / 35266
• FlyBaseID: FBgn0000529
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_004088.2
• Gene: EMX1 / 2016
• HGNCID: 3340
• Length: 290
• Species: Homo sapiens
• Alignment Length: 342
• Identity: 84/342 - (24%)
• Similarity: 118/342 - (34%)
• Gaps: 111/342 - (32%)

  Fly     7 ASLSPADAHAHANATTPTHSKAAAMASATTML--TTKTPFSIEHILFQNLNSASNNNNSSDTNGI 69
            |..:|..|.|......|.........:|.||.  ..|..|:||.::      |.:......|.|.
Human     4 AGCTPRKAAAPGRGALPRARLPRTAPAAATMFQPAAKRGFTIESLV------AKDGGTGGGTGGG 62

  Fly    70 AANTNNYAPKSSRNAVKSARSAFAHDNNPHKHPSQHSHPPQSHPPASASASATATARSNQAASGY 134
            .|.::..|..:|...::               |:..::|   ||  ||:.:|..:.....||:|
Human    63 GAGSHLLAAAASEEPLR---------------PTALNYP---HP--SAAEAAFVSGFPAAAAAG- 106

  Fly   135 AGEDYGKSMHSTPR------SNH-----HSRHGTSHYNGDQISQQLGSGAAQHPPVPTTQPQPPP 188
                .|:|::..|.      .||     |..|            |||:...|            |
Human   107 ----AGRSLYGGPELVFPEAMNHPALTVHPAH------------QLGASPLQ------------P 143

  Fly   189 PPPLNGGSGASNGVLYP---NAPYTDHGFLQMTLGYLSPSSGTYKSVDPYFLSQASLFGGAPFFG 250
            |....|.........||   ...:..|.|               ::.|   :.|..|....||..
Human   144 PHSFFGAQHRDPLHFYPWVLRNRFFGHRF---------------QASD---VPQDGLLLHGPFAR 190

  Fly   251 APGCVPELALGLGMGVNALRHCRRRKARTVFSDPQLSGLEKRFEGQRYLSTPERVELATALGLSE 315
            .|                      ::.||.||..||..||:.||...|:...||.:||.:|.|||
Human   191 KP----------------------KRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSE 233

  Fly   316 TQVKTWFQNRRMKHKKQ 332
            ||||.||||||.|:|:|
Human   234 TQVKVWFQNRRTKYKRQ 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsh	NP_477350.2	Homeodomain	275..331	CDD:459649	30/55 (55%)
EMX1	NP_004088.2	Homeodomain	193..249	CDD:459649	30/55 (55%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	249..290		1/2 (50%)