Protein Alignment bsh and DLX5

DIOPT Version :10

• Sequence 1: NP_477350.2
• Gene: bsh / 35266
• FlyBaseID: FBgn0000529
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_005212.1
• Gene: DLX5 / 1749
• HGNCID: 2918
• Length: 289
• Species: Homo sapiens
• Alignment Length: 273
• Identity: 76/273 - (27%)
• Similarity: 110/273 - (40%)
• Gaps: 107/273 - (39%)

  Fly   171 SGAAQHPPVPTTQPQPPPPPPLNGGSGASNGVLYP---NAPYTDHGFLQMTLGYLSPSSGTY-KS 231
            :.||.|.|   :|..|..|.     |.|::...|.   .||:          ||.||:|.:| |:
Human    23 TSAAMHHP---SQESPTLPE-----SSATDSDYYSPTGGAPH----------GYCSPTSASYGKA 69

  Fly   232 VDPY-----------------------FLSQASLFGGAPFFGAPGCV---------PELALGLGM 264
            ::||                       :.|....:||| :...|...         ||:.:
Human    70 LNPYQYQYHGVNGSAGSYPAKAYADYSYASSYHQYGGA-YNRVPSATNQPEKEVTEPEVRM---- 129

  Fly   265 GVNALRHCRRRKARTVFSDPQLSGLEKRFEGQRYLSTPERVELATALGLSETQVKTWFQNRRMKH 329
             ||. :..:.||.||::|..||:.|::||:..:||:.|||.|||.:|||::||||.||||:|.|.
Human   130 -VNG-KPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNKRSKI 192

  Fly   330 KKQLRRRDNANEPVDFSRSEPGKQPGEATSSSGD----------------------SKHGKLNPG 372
            ||.::.               |:.|.|.:.||.|                      |.|...:|
Human   193 KKIMKN---------------GEMPPEHSPSSSDPMACNSPQSPAVWEPQGSSRSLSHHPHAHP- 241

  Fly   373 SVGGTPTQPTSEQ 385
                    |||.|
Human   242 --------PTSNQ 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsh	NP_477350.2	Homeodomain	275..331	CDD:459649	31/55 (56%)
DLX5	NP_005212.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..49		9/33 (27%)
		DLL_N	32..118	CDD:463567	22/101 (22%)
		Homeodomain	138..194	CDD:459649	31/55 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	198..251		13/73 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	270..289