Protein Alignment bsh and DLX2

DIOPT Version :10

• Sequence 1: NP_477350.2
• Gene: bsh / 35266
• FlyBaseID: FBgn0000529
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_004396.1
• Gene: DLX2 / 1746
• HGNCID: 2915
• Length: 328
• Species: Homo sapiens
• Alignment Length: 292
• Identity: 80/292 - (27%)
• Similarity: 111/292 - (38%)
• Gaps: 80/292 - (27%)

  Fly   143 MHST---PRSNHHSRHGTSHYNGDQISQQLGSGAAQHPPVPTTQPQPPPPPPLN----------- 193
            ||||   ..|.:|.........|........|.::.|      :||..|..|::
Human    12 MHSTQIAASSTYHQHQQPPSGGGAGPGGNSSSSSSLH------KPQESPTLPVSTATDSSYYTNQ 70

  Fly   194 ---GGSGASNGVLYP-------------NAPYTDHGFLQMTLGYLSPSSGTYKSVDPYFLSQASL 242
               .|.|...|..|.             |.||:...  ...|||    :..|.|..||..|
Human    71 QHPAGGGGGGGSPYAHMGSYQYQASGLNNVPYSAKS--SYDLGY----TAAYTSYAPYGTS---- 125

  Fly   243 FGGAPFFGAP---GCVPELALGLGMGVNALRHCRRRKARTVFSDPQLSGLEKRFEGQRYLSTPER 304
              .:|....|   ...||:.:     ||. :..:.||.||::|..||:.|::||:..:||:.|||
Human   126 --SSPANNEPEKEDLEPEIRI-----VNG-KPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPER 182

  Fly   305 VELATALGLSETQVKTWFQNRRMKHKKQLRRRDNANE------------------PVDFSRSEPG 351
            .|||.:|||::||||.||||||.|.||..:..:..:|                  |..:....|.
Human   183 AELAASLGLTQTQVKIWFQNRRSKFKKMWKSGEIPSEQHPGASASPPCASPPVSAPASWDFGVPQ 247

  Fly   352 KQPGEATSSSGDSKHGKLNPGSVGGTPTQPTS 383
            :..|.....||.|     ..||.|.:|:...|
Human   248 RMAGGGGPGSGGS-----GAGSSGSSPSSAAS 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsh	NP_477350.2	Homeodomain	275..331	CDD:459649	32/55 (58%)
DLX2	NP_004396.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	16..81		11/70 (16%)
		DLL_N	51..132	CDD:463567	19/92 (21%)
		Homeodomain	153..209	CDD:459649	32/55 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	211..270		10/63 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	300..328