Protein Alignment bsh and DLX1

DIOPT Version :10

• Sequence 1: NP_477350.2
• Gene: bsh / 35266
• FlyBaseID: FBgn0000529
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_835221.2
• Gene: DLX1 / 1745
• HGNCID: 2914
• Length: 255
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 84/281 - (29%)
• Similarity: 117/281 - (41%)
• Gaps: 59/281 - (20%)

  Fly   142 SMHSTPRSNHHSRHGTSHYNGDQISQQLGSGAAQHPPVPTTQPQPPPPPPLNGGSGA-----SNG 201
            :|.:.|.|.:      |..:|..:..:.|      ||     .|...|.|::.|..:     |.|
Human     2 TMTTMPESLN------SPVSGKAVFMEFG------PP-----NQQMSPSPMSHGHYSMHCLHSAG 49

  Fly   202 VLYPNAPYTDHGFLQMTLGYLSPSSGTYKSVDPYFLSQASLFGGAPFFGA----PGCVPELAL-- 260
            ...|:..|:........|||...:|.:..:..||..|..|..|.|....:    ||...|.:.
Human    50 HSQPDGAYSSASSFSRPLGYPYVNSVSSHASSPYISSVQSYPGSASLAQSRLEDPGADSEKSTVV 114

  Fly   261 --------GLGMGVNALRHCRRRKARTVFSDPQLSGLEKRFEGQRYLSTPERVELATALGLSETQ 317
                    |.|..:        ||.||::|..||..|.:||:..:||:.|||.|||.:|||::||
Human   115 EGGEVRFNGKGKKI--------RKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQ 171

  Fly   318 VKTWFQNRRMKHKKQLRRRDNANEPV------DFSRSEPGKQPG-EATSSSGDSKHGKLNPGSV- 374
            ||.||||:|.|.||.:::...|.|..      ..|...|...|| ...||||....|  |.||.
Human   172 VKIWFQNKRSKFKKLMKQGGAALEGSALANGRALSAGSPPVPPGWNPNSSSGKGSGG--NAGSYI 234

  Fly   375 -GGTPTQPTSEQQLQMCLMQQ 394
             ..|...|::.|:    .|||
Human   235 PSYTSWYPSAHQE----AMQQ 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsh	NP_477350.2	Homeodomain	275..331	CDD:459649	31/55 (56%)
DLX1	NP_835221.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38		11/52 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	95..118		3/22 (14%)
		Homeodomain	129..185	CDD:459649	31/55 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	204..230		9/27 (33%)