Protein Alignment bsh and NKX6-3

DIOPT Version :10

• Sequence 1: NP_477350.2
• Gene: bsh / 35266
• FlyBaseID: FBgn0000529
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_001351770.1
• Gene: NKX6-3 / 157848
• HGNCID: 26328
• Length: 265
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 72/261 - (27%)
• Similarity: 111/261 - (42%)
• Gaps: 39/261 - (14%)

  Fly   156 GTSHYNGDQISQ--QLGSGAAQHPPVPTTQPQPPP--PPPLNGGS------------GASNGVLY 204
            ||...|...::|  ::.:...|:....:.....||  .|.|..|:            .|.|..|.
Human     7 GTFLLNNTPLAQFPEMKAPVCQYSVQNSFYKLSPPGLGPQLAAGTPHGITDILSRPVAAPNNSLL 71

  Fly   205 PNAPY-TDHGFLQMTLGYLSPSSGTY-KSVDPYFLSQASLFG--GAPFFGAPGC--VPELALGLG 263
            ...|: ...|.|.....|.||..|.: |:.:.|.....:.:.  |..:.|...|  .|:   .|.
Human    72 SGYPHVAGFGGLSSQGVYYSPQVGNFSKAGNEYPTRTRNCWADTGQDWRGGRQCSNTPD---PLS 133

  Fly   264 MGVNALRHCRRRKARTVFSDPQLSGLEKRFEGQRYLSTPERVELATALGLSETQVKTWFQNRRMK 328
            ..::..:|     .|..|:..|:..|||.||..:||:.|||..||.:||::|:|||.||||||.|
Human   134 DSIHKKKH-----TRPTFTGHQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTK 193

  Fly   329 HKKQLRRRDNANEPVDFSRSEPGKQPGEATSSSGDSKHGKLNPGSVGGTPTQPTSEQQLQMCLMQ 393
            .:|:     :|.||   |.|.| :.||.|.:.:|..:....|.......|..|.|:.:....|::
Human   194 WRKK-----SALEP---SSSTP-RAPGGAGAGAGGDRAPSENEDDEYNKPLDPDSDDEKIRLLLR 249

  Fly   394 Q 394
            :
Human   250 K 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsh	NP_477350.2	Homeodomain	275..331	CDD:459649	28/55 (51%)
NKX6-3	NP_001351770.1	Homeodomain	138..196	CDD:459649	29/62 (47%)