DRSC/TRiP Functional Genomics Resources

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Protein Alignment bsh and Hoxb3

DIOPT Version :10

Sequence 1:NP_477350.2 Gene:bsh / 35266 FlyBaseID:FBgn0000529 Length:429 Species:Drosophila melanogaster
Sequence 2:NP_034588.2 Gene:Hoxb3 / 15410 MGIID:96184 Length:433 Species:Mus musculus


Alignment Length:307 Identity:91/307 - (29%)
Similarity:112/307 - (36%) Gaps:87/307 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   123 ATARSNQAASGYAGEDYGKSMHSTPRSNHHSRHG--------TSHYNGD-QIS----QQLG---- 170
            ||...|.||:.:.|      ..|.|.||.....|        .:|..|| |.|    |.||    
Mouse     4 ATYYDNTAAALFGG------YSSYPGSNGFGYDGPPQPPFQAATHLEGDYQRSACSLQSLGNAAP 62

  Fly   171 -------SGAAQHPPV-PTTQPQPP--PPPPL----------NGGSGASNGVLYP-------NAP 208
                   :|:...|.: |...|.||  |||..          |||..:.:|   |       |:.
Mouse    63 HAKSKELNGSCMRPGLAPEPLPAPPGSPPPSAAPTSTTSNSNNGGGPSKSG---PPKCGAGSNST 124

  Fly   209 YTDHGFLQMTLGYLSPSSGTYKSVDPYFLSQASLFGGAPFFGAPGCVPELALGLGMGVNALR--- 270
            .|...|..|.   .|..:...|:..|.........||....|..|.......|.|.|....:   
Mouse   125 LTKQIFPWMK---ESRQTSKLKNSSPGTAEGCGGGGGGGGGGGGGGGGSSGGGGGGGGGGDKSPP 186

  Fly   271 -HCRRRKARTVFSDPQLSGLEKRFEGQRYLSTPERVELATALGLSETQVKTWFQNRRMKHKKQLR 334
             ....::|||.::..||..|||.|...|||..|.|||:|..|.|||.|:|.||||||||:||.  
Mouse   187 GSAASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKD-- 249

  Fly   335 RRDNANEPVDFSRSEPGKQPGEATSSSGDSKHGKLNPGSVGGTPTQP 381
                            .|..|.|:||.|.|.         .|:|.||
Mouse   250 ----------------QKAKGLASSSGGPSP---------AGSPPQP 271

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
bshNP_477350.2 Homeodomain 275..331 CDD:459649 31/55 (56%)
Hoxb3NP_034588.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 63..124 15/63 (24%)
Antp-type hexapeptide 129..134 1/4 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 136..195 10/58 (17%)
Homeodomain 192..248 CDD:459649 31/55 (56%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 249..276 11/50 (22%)
DUF4074 369..431 CDD:463833
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 389..433
Blue background indicates that the domain is not in the aligned region.

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