Protein Alignment bsh and Nkx6-2

DIOPT Version :10

• Sequence 1: NP_477350.2
• Gene: bsh / 35266
• FlyBaseID: FBgn0000529
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_899071.2
• Gene: Nkx6-2 / 14912
• MGIID: 1352738
• Length: 277
• Species: Mus musculus
• Alignment Length: 314
• Identity: 85/314 - (27%)
• Similarity: 119/314 - (37%)
• Gaps: 81/314 - (25%)

  Fly   111 SHPPASASASATATARSNQAASGYAGEDY---GKSMHSTPRSNHHSRH---GTSHYNGDQISQQL 169
            :.|.|...:||...|..|.|....:...|   |.:...||........   ||.|    .||..|
Mouse     4 NRPGAFVLSSAPLAALHNMAEMKTSLFPYALQGPAGFKTPALGSLGAQLPLGTPH----GISDIL 64

  Fly   170 GSGAAQHPPVPTTQPQPPPPPPLNGGSGASNGVLYPNAPYTDHGFLQMTLGYLSPSSGTYKSVDP 234
            |.      ||                 ||:.|.|..:.|.. :|.......|..|::...:.
Mouse    65 GR------PV-----------------GAAGGGLLGSLPRL-NGLASSAGVYFGPAAAVARG--- 102

  Fly   235 YFLSQASLFGGAPFF------GAPGCVPELALGLGMGVNALRHCRRRKARTVFSDPQLSGLEKRF 293
            |....|.|.|..|.|      |:|...|.||.....|....:..:::.:|..||..|:..|||.|
Mouse   103 YPKPLAELPGRPPIFWPGVVQGSPWRDPRLAGSAQAGGVLDKDGKKKHSRPTFSGQQIFALEKTF 167

  Fly   294 EGQRYLSTPERVELATALGLSETQVKTWFQNRRMKHKKQLRRRDNANEPVDFSRSEPGKQPGEAT 358
            |..:||:.|||..||.:||::|:|||.||||||.|.:|:     :|.|.....:.:
Mouse   168 EQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKR-----HAAEMASAKKKQ--------- 218

  Fly   359 SSSGDSKHGKLNPGSVGGTPTQPTSEQQLQMCLMQQGYSTDDYS-DLEADSGDE 411
                ||...||   .|||:..:                ..|:|: .|:.:|.||
Mouse   219 ----DSDAEKL---KVGGSDAE----------------DDDEYNRPLDPNSDDE 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsh	NP_477350.2	Homeodomain	275..331	CDD:459649	29/55 (53%)
Nkx6-2	NP_899071.2	Homeodomain	147..205	CDD:459649	29/57 (51%)